Figure 30-1. Schematic representing the pathophysiology of erectile dysfunction after radical prostatectomy. *Apoptosis occurs in nerves, smooth muscle, and endothelium as a result of neural trauma. APA accessory pudendal artery,…

Stage of the sexual response cycle Women Men Desire Bupropion Bupropion Flibanserin Ropinirole Melanocortin Testosterone Arousal   Alprostadil Apomorphine Apomorphine Buspirone Bupropion Sildenafil Melanocortin PDE5 inhibitors Yohimbine Orgasm Bupropion Bupropion…

Type Mechanisms Examples Direct Change in sexual desire from disease Typically reduced, e.g., from high prolactin and anemia of chronic renal failure [1]. May be increased, e.g., from some brain…

Figure 17-1. Physiology of ejaculation . The ejaculation reflex and ejaculatory control. Ejaculation is the result of the coordinated contractile activity involving different ejaculatory organs organized by the spinal ejaculatory…

1966—Masters and Johnson’s Sexual Response Model [131] This linear model focuses on genital and peripheral physiological changes and on the classification of sexual dysfunctions based on designated functional stages. Interest…

A. A persistent or recurrent pattern of ejaculation occurring during partnered sexual activity within approximately 1 min following vaginal penetration and before the individual wishes it. Note: Although the diagnosis…

Substance type Examples Arousal and/or erection Orgasmic function Antihypertensives α- and β-blockers, sympathetic inhibitors x x Antidepressants SSRIs, MAOIs, tricyclics x x Antipsychotics Phenothiazines, thioxanthenes x x Antiepileptics Gabapentin, topiramate,…