Fig. 16.1 Representative cardiac 123I-metaiodobenzylguanidine (MIBG) scintigraphy findings in patients with dementia with Lewy bodies (DLB) and Alzheimer’s disease (AD). Delayed cardiac MIBG scintigraphy showed significant decreased accumulation of MIBG…
Fig. 13.1 Structural formula of (a) noradrenaline, (b) meta-iodobenzylguanidine (MIBG), (c) guanethidine, and (d) bretylium. MIBG was synthesized on the basis of the structural formulas of guanethidine and bretylium 13.2…
Locus Inheritance Gene Cardiac MIBG uptake Lewy bodies PARK1 AD SNCA mutation Reduced + PARK2 AR Parkin Normal − PARK4 AD SNCA multiplication Reduced + PARK6 AR PINK1 Reduced or…
Fig. 8.1 Polygraphic recordings of Cheyne-Stokes respiration in a patient with congestive heart failure in 180 s. From top to bottom, electrocardiogram, oronasal flow, ribcage motion, and arterial oxygen saturation on…
Fig. 14.1 Structures of gamma camera and the effect of high-energy photons penetration between low-energy collimator and medium-energy collimator on the results of heart-to-mediastinum ratio. 123I emits not only 159 keV…
Fig. 6.1 Increases in burst intensity: potential mechanisms. Schematic representation of the three mechanisms that can bring about an increase in sympathetic burst intensity 6.2 Assessment of Multiunit MSNA 6.2.1…
Fig. 19.1 Immunohistochemical staining of the epicardial nerve fascicles from Parkinson’s disease and a wide range of neurodegenerative disorders. Tyrosine hydroxylase (TH)- and neurofilament (NF)-immunoreactive axons were markedly decreased in…
© Springer Japan 2017Satoshi Iwase, Junichiro Hayano and Satoshi Orimo (eds.)Clinical Assessment of the Autonomic Nervous System10.1007/978-4-431-56012-8_12 12. An Introduction to MIBG Cardiac Scintigraphy Satoshi Orimo1 (1) Division of Neurology, Kanto Central Hospital of the Mutual Aid…
Fig. 1.1 Muscle sympathetic nerve activity (MSNA) and blood pressure. From the top to the bottom, original multi-fiber burst of MSNA, microneurographically recorded from the tibial nerve in a healthy…
