Sex-Hormone Treatment Andrew G. Herzog Introduction There is considerable scientific evidence at molecular biologic, neuronal, experimental animal, and clinical levels to indicate that reproductive steroids have neuroactive properties that play…
Ketogenic Diet Carl E. Stafstrom Eileen P. G. Vining Jong M. Rho Introduction The ketogenic diet (KD) is a high-fat, low-carbohydrate, adequate-protein diet that has been used as an alternative…
Prophylactic Treatment L. James Willmore Introduction Because antiepileptic drugs (AEDs) target brain structures for their effect, they are being used to treat several neurologic conditions other than epilepsy. While control…
Drug-resistant Epilepsy Warren T. Blume Introduction This chapter discusses some factors that promote antiepileptic drug-resistant epilepsy in 20% to 30% of patients who have seizure disorders. Accurate and prompt recognition…
Treatment of Status Epilepticus Brian K. Alldredge David M. Treiman Thomas P. Bleck Simon D. Shorvon Introduction Status epilepticus (SE) is a medical emergency that requires immediate and vigorous treatment…
Treatment of Provoked Seizures Braxton B. Wannamaker Harold E. Booker Introduction Provoked seizures are usually contrasted with “spontaneous” seizures. In reality, no seizures are truly spontaneous, as all result from…
Treatment of Febrile Seizures Peter R. Camfield Carol S. Camfield Kai J. Eriksson Introduction From a biologic perspective, febrile seizures are virtually always benign. However, they are frightening for parents…
Treatment of Neonatal Seizures Eli M. Mizrahi Mark S. Scher Introduction The overall goal of treatment of neonatal seizures is to minimize brain injury that may be associated with or…
Treatment of Single and Infrequent Seizures Ettore Beghi Anne T. Berg Shlomo Shinnar W. Allen Hauser Introduction Epilepsy is a treatable condition characterized by the occurrence of repeated unprovoked seizures….
Adjunctive and Combination Therapy Blaise F.D. Bourgeois Frank Gilliam Introduction A historical review of the practices of predominant combination therapy versus predominant monotherapy in the medical treatment of epilepsy reveals…
