Serotype Natural host/origin Optimal organ/tissue/cell type transduced CNS area transduced Receptor Coreceptor Blood–brain barrier penetration Disease targets AAV1 Monkey Muscle [39], Liver [110], CNS [32, 42] SNpc, SNpr, midbrain, hippocampus…
Fig. 1 (a) Nine copies of Epo HRE consensus sequence. The HIF-1 binding sites are underlined. (b) Schematic drawing of H9LacZ and H9VEGF. Nine copies of Epo HRE (9HRE) were…
Author (reference) Animal System Age/injection site Proliferation (RTK/KRAS/PI3K) Apoptosis (p53/ARF) Cell cycle (Rb/INK4) Best combined penetrance Holland et al. 2000 [13] Mice RCAS Neonatal/R frontal AKT, KRAS 26 % Dai…
Fig. 1 Behavioral tests for the functional recovery after rubrospinal tract transection. (a) Photo showing the symmetrical use of both forelimbs of the rat during vertical exploration of the cylinder…
