Genetics of Amyotrophic Lateral Sclerosis
Abstract The identification of disease-causing mutations has proven to be essential for our understanding of the pathogenesis and progression of human disorders. The identification of such genes can lead to…
Natural History of Amyotrophic Lateral Sclerosis
Abstract Amyotrophic lateral sclerosis (ALS) is the most common adult-onset motor neuron disease. ALS was first described in the medical literature in the mid-19th century, but despite its early recognition…
