Molecular Biology of Neuroendocrine Tumors
Fig. 4.1 In NETs, the study of inherited syndromes allowed the identification of the common deregulation of genes involved in the mTOR pathway in these tumors. As a master regulator…
Genetic Syndromes Associated with Neuroendocrine Tumours
Name Neuroendocrine tumor (NET) (frequency) MEN-1 syndrome (MEN-1) (MIM 131100) Pituitary adenoma (5–65 %) (Wermer’s syndrome) Pancreatic NET (80–100 %) Thymic NET (mostly ♂), (<10 %) Lung NET (20–25 %)…
Overview of Gastrointestinal Neuroendocrine Tumours
Foregut carcinoids Midgut carcinoids Hindgut carcinoids Thymus Jejunum Transverse colon Bronchus Ileum Descending colon Stomach Ascending colon Sigmoid colon Duodenum Caecum Rectum Appendix Genitourinary tract The ENETS classification 2006/2007, the…
