Introduction and History
1 Introduction and History Neurofibromatosis * is the umbrella term for three distinct genetic disorders that share a hallmark manifestation—tumor growth in the tissues that surround nerves. Most tumors are…
Cognitive Function and Learning Disabilities in Neurofibromatosis 1
8 Cognitive Function and Learning Disabilities in Neurofibromatosis 1 Neurofibromatosis 1 (NF1) impacts brain development in ways that researchers are still trying to understand. About half of all people with…
Genetics and Genetic Counseling in Neurofibromatosis 1 and Neurofibromatosis 2
4 Genetics and Genetic Counseling in Neurofibromatosis 1 and Neurofibromatosis 2 Molecular genetics explains how a mutation may cause a disorder. Clinical genetics takes a somewhat different perspective: how the…
Other Neural Tumors and Nervous System Abnormalities in Neurofibromatosis 1
7 Other Neural Tumors and Nervous System Abnormalities in Neurofibromatosis 1 As would be expected in a disorder caused by the loss of a tumor suppressor gene, neurofibromatosis 1 (NF1)…
