Vigabatrin (Sabril)

Nov 3, 2016 by in NEUROLOGY Comments Off on Vigabatrin (Sabril)

Fig. 29.1 Vigabatrin neurotoxicity. An infant with a history of tuberous sclerosis treated with vigabatrin presented with lethargy. Axial T2-weighted MR images (panel a), DWI (panel b), and ADC maps…

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Topical Prostaglandin Analogues

Nov 3, 2016 by in NEUROLOGY Comments Off on Topical Prostaglandin Analogues

Fig. 54.1 Prostaglandin-associated periorbitopathy. The patient has a history of the left eye only Lumigan use for a number of years and had left enophthalmos along with superior sulcus deformity…

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Dilantin (Phenytoin Sodium)

Nov 3, 2016 by in NEUROLOGY Comments Off on Dilantin (Phenytoin Sodium)

Fig. 27.1 Cerebellar atrophy related to phenytoin use. Coronal T2-weighted (a) and sagittal T1-weighted (b) MR images demonstrate disproportionate diffuse cerebellar atrophy Another neurological effect of phenytoin is a transient…

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Hypertonic Saline

Nov 3, 2016 by in NEUROLOGY Comments Off on Hypertonic Saline

Fig. 36.1 Osmotic demyelination related to rapid correction of hyponatremia with hypertonic saline. Axial FLAIR (a, b), axial DWI (c, d), and axial ADC maps (e, f) show a trident-shaped…

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Gadolinium-Based Contrast Agents

Nov 3, 2016 by in NEUROLOGY Comments Off on Gadolinium-Based Contrast Agents

Fig. 13.1 Biodistribution of extracellular gadolinium-based contrast agents. Normal non-contrast T1 image (a) and corresponding post-contrast fat-suppressed T1 image (b) obtained with intravenous administration of MultiHance show expected enhancement within…

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Acetominophen (Tylenol, Paracetamol)

Nov 3, 2016 by in NEUROLOGY Comments Off on Acetominophen (Tylenol, Paracetamol)

Fig. 49.1 Cerebral edema secondary to fulminant acute liver failure associated with acetaminophen overdose. Axial CT image obtained at the time of presentation soon after ingestion (a) demonstrates an unremarkable…

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Vaccines

Nov 3, 2016 by in NEUROLOGY Comments Off on Vaccines

Fig. 48.1 ADEM related to vaccination. Axial FLAIR images (a–f) obtained approximately 2 weeks after the administration of the vaccine demonstrate numerous hyperintense foci (arrows) involving the infratentorial and supratentorial…

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Recombinant Human Bone Morphogenetic Protein

Nov 3, 2016 by in NEUROLOGY Comments Off on Recombinant Human Bone Morphogenetic Protein

Fig. 52.1 rhBMP-induced osteolysis and heterotopic bone formation. Initial postoperative sagittal CT image (a) shows unremarkable vertebral bodies adjacent to the intervertebral disc spacers. Follow-up sagittal CT image (b) shows…

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