CHAPTER 79 ACUTE DISSEMINATED ENCEPHALOMYELITIS AND PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY Richard T. Johnson Viral infections lead to a variety of demyelinating diseases of the central and peripheral nervous systems in animals…
CHAPTER 8 COMA AND BRAIN DEATH Jeffrey V. Rosenfeld, Peter J. Lennarson Assessing the level of consciousness and diagnosing the cause of coma are fundamental aspects of medical practice. Consciousness…
CHAPTER 3 DISORDERS OF LANGUAGE Michael M. Saling There are two main schools of thought in the history of neurogenic language disorders, both of which have relevance to modern aphasiology….
CHAPTER 49 DEVELOPMENTAL DEFECTS AND PATHOPHYSIOLOGY Maxime Guye, Patrick Chauvel Developmental defects are among the most frequent causes of epilepsy, particularly of refractory epilepsy. They constitute a very broad range…
CHAPTER 66 AMYOTROPHIC LATERAL SCLEROSIS Kevin B. Boylan BACKGROUND Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder causing stereotypic motor impairment, commonly known in the United States as Lou…
CHAPTER 67 HUNTINGTON’S DISEASE Erika Driver-Dunckley, John N. Caviness Huntington’s disease is an autosomal dominant, progressive neurodegenerative disease that typically manifests in adulthood. The prevalence is estimated at 5 to…
CHAPTER 76 CLINICAL SPECTRUM: DEFINITION AND NATURAL PROGRESSION Rajas Deshpande, Marcelo Kremenchutzky, George P.A. Rice Once a neurological illness common in the Western and developed world, multiple sclerosis (MS) is…
CHAPTER 95 PRION DISEASES Katherine Murray, Robert G. Will Although the human forms of prion disease, including Creutzfeldt-Jakob disease (CJD), are rare, this group of fatal disorders of the central…
CHAPTER 63 HYDROCEPHALUS, INCLUDING NORMAL-PRESSURE HYDROCEPHALUS Noojan J. Kazemi, Andrew H. Kaye, Elsdon Storey Hydrocephalus is an abnormal enlargement of the ventricles caused by an excessive accumulation of cerebrospinal fluid…
CHAPTER 84 INFECTIVE NEUROPATHIES Joshua Kershen, Thomas Sabin While most peripheral neuropathies encountered by the clinical neurologist will have toxic or metabolic etiologies, it is very important to consider that…
