Abstract Electroencephalography (EEG) or amplitude-integrated EEG (aEEG) provides important information on brain function in newborns. It can detect subclinical seizures and assess the effect of antiepileptic medication, and the background…
Abstract Congenital heart disease (CHD) is the most common malformation in humans. The psychomotor development of children with CHD has been shown to be delayed in many aspects throughout adulthood….
Abstract Neonatal hypotonia can be caused by diseases that impair both the central and the peripheral nervous systems; it represents a diagnostic challenge to both the experienced neonatologist and pediatric…
Abstract Neonatal care is continually changing. There is increasing evidence that these advances work together to produce incremental improvements in outcome, promoting survival of children without serious impairment. Thus major…
Abstract Bacterial meningitis occurs in approximately 0.4 neonates per 1000 live births. Virtually all organisms that cause neonatal infection or sepsis can result in central nervous system disease with severe…
Abstract Starting in the 1950s through the 1980s, clinical practice has evolved to essentially eliminate classic kernicterus. Great strides have been made in the management of neonatal jaundice, hyperbilirubinemia, and…
Abstract Bacterial meningitis occurs in approximately 0.4 neonates per 1000 live births. Virtually all organisms that cause neonatal infection or sepsis can result in central nervous disease with severe consequences…
Abstract The past decade has witnessed a major transformation in our understanding of epilepsies presenting in the neonatal period. Old broad umbrella syndromes, such as Ohtahara syndrome and early myoclonic…
Abstract Glucose homeostasis is the foundation of energy supply and maintenance during the transition period of fetal to newborn life. Despite this important position, our understanding of its vital role…
Abstract Stroke is a common neurologic disorder in the neonatal period that results in significant morbidity. This chapter discusses the classification, epidemiology, and clinical presentation of arterial, venous, and hemorrhagic…
