Blockade of Interleukin-6 Effects on Cytokine Profiles and Macrophage Activation After Spinal Cord Injury in Mice

Mar 11, 2017 by in NEUROSURGERY Comments Off on Blockade of Interleukin-6 Effects on Cytokine Profiles and Macrophage Activation After Spinal Cord Injury in Mice

Fig. 17.1 Histological and behavioral evaluation after anti-interleukin (IL)-6 receptor (MR16-1) treatment. Luxol fast blue (LFB) stained axial sections at the injury epicenter (42 days post-injury) showed remarkable reduction in…

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Axonal Regeneration Across an Artificial Scaffold Combined with Cell Transplantation Applied to the Transected Spinal Cord

Mar 11, 2017 by in NEUROSURGERY Comments Off on Axonal Regeneration Across an Artificial Scaffold Combined with Cell Transplantation Applied to the Transected Spinal Cord

Fig. 22.1 Appearance of honeycomb collagen sponge (HC) and in vitro evaluation of dorsal root ganglions (DRGs) on HC. HC consists of serial tunnel structures resembling a honeycomb (A). HC…

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Targeted Retrograde Gene Delivery into the Injured Spinal Cord Using Recombinant Adenovirus Vector Carrying Neurotrophic Factor Gene

Mar 11, 2017 by in NEUROSURGERY Comments Off on Targeted Retrograde Gene Delivery into the Injured Spinal Cord Using Recombinant Adenovirus Vector Carrying Neurotrophic Factor Gene

Fig. 16.1 Targeted retrograde gene delivery of recombinant adenovirus vector-mediated LacZ gene through the sternomastoid muscle innervated by spinal accessory nerves. (a) Lower magnification, (b–d) high-power photomicrograph of the box…

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The Effects of Mesenchymal Stem Cell-Transduced Multineurotrophin to Improve Function Following Spinal Cord Injury

Mar 11, 2017 by in NEUROSURGERY Comments Off on The Effects of Mesenchymal Stem Cell-Transduced Multineurotrophin to Improve Function Following Spinal Cord Injury

Fig. 21.1 Diagram of the GFP, MNTS1, and MNTS1/p75− lentivirus vectors We monitored the locomotor functional recovery in all four groups: control, MSC, MSC-MNTS1, and MSC-MNTS1/p75−, respectively, using the BBB…

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Morphological Changes in Anterior Horn Cells, Immunoreactivity to Neurotrophic Factors, and Neuronal Cell Death of Spinal Cord Lesions in the Spinal Hyperostotic Mouse (twy/twy) with Chronic Mechanical Cord Compression

Mar 11, 2017 by in NEUROSURGERY Comments Off on Morphological Changes in Anterior Horn Cells, Immunoreactivity to Neurotrophic Factors, and Neuronal Cell Death of Spinal Cord Lesions in the Spinal Hyperostotic Mouse (twy/twy) with Chronic Mechanical Cord Compression

Fig. 9.1 Photomicrographs showing wheat germ agglutinin-horseradish peroxidase-labeled spinal accessory motoneurons. (a) A motoneuron at C2–C3 segments in a representative control ICR mouse; (b) site A in the twy mouse,…

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