Investigational Therapies for Brain Metastases

Oct 13, 2017 by in NEUROSURGERY Comments Off on Investigational Therapies for Brain Metastases

Contrary to the incidence of primary cancers, the incidence of brain metastasis has been increasing. This increase is likely because of the effects of an aging population, improved neuroimaging surveillance,…

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Leptomeningeal Disease

Oct 13, 2017 by in NEUROSURGERY Comments Off on Leptomeningeal Disease

Leptomeningeal metastasis (LMD) is a lethal complication caused by a variety of cancers, typically developing late in the disease course. It is associated with major neurologic disabilities and short survival….

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Surgical Management of Brain Metastases

Oct 13, 2017 by in NEUROSURGERY Comments Off on Surgical Management of Brain Metastases

In the past 20 years, surgical resection has found an established role in the management of metastatic brain tumors. Several factors, however, make strong evidence-based medicine impossible to provide for…

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Radiosurgical Management of Brain Metastases

Oct 13, 2017 by in NEUROSURGERY Comments Off on Radiosurgical Management of Brain Metastases

Stereotactic radiosurgery (SRS) should be considered in the comprehensive treatment paradigm for all patients with brain metastases. This technique has proven benefits for local tumor control in individuals with as…

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Management of Skull Base Metastases

Oct 13, 2017 by in NEUROSURGERY Comments Off on Management of Skull Base Metastases

Skull base metastases (SBM) are rare among all tumors affecting the base of the skull. Because of their rarity, they have received limited attention in the published medical literature. Several…

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Radiotherapy for Brain Metastases

Oct 13, 2017 by in NEUROSURGERY Comments Off on Radiotherapy for Brain Metastases

Brain metastases affect 20% to 40% of patients with cancer and are the most common intracranial tumor in adults. The optimal treatment of brain metastases remains controversial. There are several…

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Medical Management of Brain Metastases

Oct 13, 2017 by in NEUROSURGERY Comments Off on Medical Management of Brain Metastases

The main objective of treating brain metastases is to improve survival and to reduce symptom burden, preserve function, and enhance quality of life. As such, concurrent local control of existing…

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