Focal cooling may provide a safe, nondestructive alternative to resective and disconnective strategies that have been proposed or used to control refractory epilepsy. Observations of the effects of direct application…
Invasive electroencephalography via subdural implanted electrodes is essential for the identification and localization of the epileptogenic focus in a large percentage of cases of medically refractory epilepsy. The implantation of…
Epilepsy is characterized by intermittent, paroxysmal, hypersynchronous electrical activity that may remain localized and/or spread and severely disrupt the brain’s normal multitask and multiprocessing function. Epileptic seizures are the hallmarks…
Many factors underlying basic epileptic conditions determine the characteristics of epileptic seizures and the therapeutic outcome. Diagnosis and treatment rely on the clinical manifestations as well as electroencephalographic (EEG) epileptic…
Deep brain stimulation (DBS) is an established treatment for Parkinson’s disease, and is increasingly used for other neuropsychiatric conditions including epilepsy. Nevertheless, neural mechanisms for DBS and other forms of…
Neurostimulation in epilepsy has witnessed a century-long evolution that has resulted in the use of neurostimulation to both modulate and suppress abnormal neuronal firing. The recent development of advanced responsive…
Neuromodulation is one of the fastest growing fields in neurosurgery, as reflected by the growing interest in the use of electrical brain stimulation (EBS) to treat drug-resistant epilepsy, pain, and…
With the growing applications for deep brain stimulators (DBS) in recent years, interest in using DBS as an option for patients with epilepsy has increased. Thalamic DBS appears to be…
Direct electrical stimulation of the brain is an increasingly popular means of treating refractory epilepsy. Although there has been moderate success in human trials, the rate of seizure freedom does…
Edward F. Chang, MD, Guest Editor Nicholas M. Barbaro, MD, Guest Editor Epilepsy is a devastating neurological disorder that afflicts nearly 1% of the population. While resective surgery has been…
