Epilogue: Perspectives and Caveats

Jun 12, 2017 by in NEUROLOGY Comments Off on Epilogue: Perspectives and Caveats

Fig. 1 Induced pluripotent stem cells strategy to orient cell development towards differentiated neurons Taking fibroblasts in patients with a genetic disease, transforming the adult cells into iPSCs and reprogramming…

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Mouse Models of Tuberous Sclerosis

Jun 12, 2017 by in NEUROLOGY Comments Off on Mouse Models of Tuberous Sclerosis

Fig. 1 The figure summarizes neurobiological processes that have been found to be abnormal in mouse models of tuberous sclerosis and that could contribute to the neuropsychiatric manifestations associated with…

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Serotonin Disturbance in Mouse Models of Autism Spectrum Disorders

Jun 12, 2017 by in NEUROLOGY Comments Off on Serotonin Disturbance in Mouse Models of Autism Spectrum Disorders

Animal models 5-HT-related abnormalities Region References Developmental hyperserotonemia model (DHS) Increase Whole (nonspecific 5-HT receptors agonist) [37, 38, 113] VPA treatment for embryo Decrease/Increase 5-HT Abnormal migration of 5-HT neurons…

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Zebrafish Social Behavior Testing in Developmental Brain Disorders

Jun 12, 2017 by in NEUROLOGY Comments Off on Zebrafish Social Behavior Testing in Developmental Brain Disorders

© Springer Science+Business Media New York 2015Pierre L. Roubertoux (ed.)Organism Models of Autism Spectrum DisordersNeuromethods10010.1007/978-1-4939-2250-5_12 12. Zebrafish Social Behavior Testing in Developmental Brain Disorders Christine Buske1   (1) Papers/Springer SBM, 236 Gray’s Inn Road – Floor…

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Communication and Language in Animals

Jun 12, 2017 by in NEUROLOGY Comments Off on Communication and Language in Animals

© Springer Science+Business Media New York 2015Pierre L. Roubertoux (ed.)Organism Models of Autism Spectrum DisordersNeuromethods10010.1007/978-1-4939-2250-5_10 10. Communication and Language in Animals Gene S. Fisch1   (1) Department of Epidemiology & Health Promotion, NYU Colleges of Dentistry &…

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Organism Models: Choosing the Right Model

Jun 12, 2017 by in NEUROLOGY Comments Off on Organism Models: Choosing the Right Model

Fig. 1 The translational approach Organism models are used in the second and third stages. The identification of infectious, traumatic, and genetic events causing a disorder is initially done on…

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