Fig. 6.1 A simplified scheme of the Sonic Hedgehog signaling pathway. PTCH patched, SHH Sonic Hedgehog protein, SMO smoothened, SUFU suppressor of fused Aberrant activity of the Shh signaling pathway…
© Springer International Publishing Switzerland 2015M. Memet Özek, Giuseppe Cinalli, Wirginia Maixner and Christian Sainte-Rose (eds.)Posterior Fossa Tumors in Children10.1007/978-3-319-11274-9_44 44. Molecular Biology and Genetics of Chordomas Mustafa Güdük1 and M. Memet Özek2 (1) Department of Neurosurgery, Acibadem University, School…
© Springer International Publishing Switzerland 2015M. Memet Özek, Giuseppe Cinalli, Wirginia Maixner and Christian Sainte-Rose (eds.)Posterior Fossa Tumors in Children10.1007/978-3-319-11274-9_43 43. Radiation Therapy in Atypical Teratoid/Rhabdoid Tumors Hale Basak Caglar1 (1) Department of Radiation Oncology, Medipol University, Istanbul, Turkey…
40. Kosaka C, Sasaguri T, Komiyama Y et al (2001) All-trans retinoic acid inhibits vascular smooth muscle cell proliferation targeting multiple genes for cyclins and cyclin dependent kinases. Hypertens Res…
Authors and year (reference) No. of patients Treatment Outcome Doz et al. (2002) [20] 19 CCNU, VCR; PCB2 + PBSC infusion × 4 courses/XRT Median survival 11 months Dunkel et…
© Springer International Publishing Switzerland 2015M. Memet Özek, Giuseppe Cinalli, Wirginia Maixner and Christian Sainte-Rose (eds.)Posterior Fossa Tumors in Children10.1007/978-3-319-11274-9_29 29. Cerebellar Astrocytoma: Oncological Care Pratiti Bandopadhayay1 , Peter A. Downie2 and David M. Ashley3 (1) Pediatric Neuro-Oncology Program, Dana-Farber Cancer Institute, Boston…
Complication Predisposing factors Preventive techniques CSF leak/pseudomeningocele Hydrocephalus wound infection Clean cuts to structurally important tissue (fascia, dura) Avoid diathermy to same Complete dural closure using galea graft or substitute…
141. Kurwale NS, Suri V, Suri A et al (2011) Predictive factors for early symptomatic recurrence in pilocytic astrocytoma: does angiogenesis have a role to play? J Clin Neurosci 18(4):472–477PubMed…
© Springer International Publishing Switzerland 2015M. Memet Özek, Giuseppe Cinalli, Wirginia Maixner and Christian Sainte-Rose (eds.)Posterior Fossa Tumors in Children10.1007/978-3-319-11274-9_24 24. Oncological Management of Ependymomas Jacques Grill1 and Maria-Jesus Lobon Iglesias1 (1) Pediatric and Adolescent Oncology, Institut Gustave Roussy, Rue…
