Autism and Dopamine
Fig. 11.1 Electrical stimulation (black bar, 25 pulses at 50 Hz, 200 µA) of the a) Purkinje cell layer (PCL) or b) dentate nucleus (DN) evokes a long lasting increase in medial…
Fig. 11.1 Electrical stimulation (black bar, 25 pulses at 50 Hz, 200 µA) of the a) Purkinje cell layer (PCL) or b) dentate nucleus (DN) evokes a long lasting increase in medial…
Fig. 16.1 The Reelin signaling cascade. Reelin binds to its extracellular receptors APOER2, VLDLR and α3β1 integrin resulting in clustering of the receptors and ephrin B proteins (ENFBs). This clustering…
Fig. 7.1 Shen et al. showed how infants and toddlers who were subsequently diagnosed with ASD had greater total cerebral volumes (after removing non brain tissue) and increased rates of growth,…
Fig. 4.1 The causes of autism spectrum disorders In current clinical practice, the diagnosis of ASDs is purely based on the behavioral assessment using various standardized screening or diagnostic tools….
Fig. 15.1 Nicotinic receptors. Graphic presentation of homomeric and heteromeric receptors and their location. Most functional nAChRs contain more than one subunit, and are therefore heteromeric. The different subunit combinations…
Fig. 8.1 Periventricular germinal cells line the ventricular cavity, seen at the bottom of the image. Asymmetric divisions of germinal cells provide for daughter cells that migrate to the cortex…
Fig. 20.1 Mechanism of generation of reactive oxygen species and oxidative stress. Leaked electrons from mitochondrial ETC complexes I and III react with molecular oxygen to produce superoxide (first free…
Fig. 14.1 Expression in the paraventricular nucleus (PVN) of OT, as measured by ICC, is reduced in Fmr1 KO mice, compared to the wild-type (WT). (Reprinted from Brain Research, Francis…
© Springer Science+Business Media New York 2015S. Hossein Fatemi (ed.)The Molecular Basis of AutismContemporary Clinical Neuroscience10.1007/978-1-4939-2190-4_19 19. Cognition, Motor Control and Other Aspects of Autism: A Pragmatic Review James W. Howell1 and Detlef H. Heck2 (1)…
© Springer Science+Business Media New York 2015S. Hossein Fatemi (ed.)The Molecular Basis of AutismContemporary Clinical Neuroscience10.1007/978-1-4939-2190-4_18 18. Neurotrophins, Their Receptors and Autism: Ligand vs. Receptor Abnormalities Elizabeth M. Sajdel-Sulkowska1 (1) Department of Psychiatry, Harvard Medical…