Resection for Uncontrolled Epilepsy in the Setting of Focal Lesions on MRI: Tumor, Vascular Malformation, Trauma, and Infarction Dennis D. Spencer Alexandre C. Carpentier Advances in neuroimaging techniques, particularly high-resolution…
Hippocampal Sclerosis and Dual Pathology Evan J. Fertig Susan S. Spencer Over the past several decades, technical advances have revolutionized the surgical treatment of medically refractory epilepsy, allowing precise localization…
Intracranial Electroencephalography and Localization Studies Selim R. Benbadis Elaine Wyllie William E. Bingaman In recent years, as new neuroimaging techniques have revealed hippocampal sclerosis, focal cortical dysplasia, and other subtle…
Metabolic and Functional Neuroimaging William D. Gaillard Functional imaging studies using radiotracers, such as positron emission tomography (PET) and single-photonemission computed tomography (SPECT), are performed to identify or confirm the…
The Intracarotid Amobarbital Procedure Max R. Trenerry David W. Loring The preoperative evaluation of patients for epilepsy surgery typically includes electroencephalographic (EEG) monitoring, magnetic resonance imaging (MRI), neurologic examination, neuropsychological…
Magnetic Resonance Imaging Techniques in the Evaluation for Epilepsy Surgery Susanne Knake P. Ellen Grant Approximately 60% of all patients with epilepsy (0.4% of the population in industrialized countries) suffer…
Recognition of Potential Surgical Candidates and Video-Electroencephalographic Evaluation Gregory D. Cascino In the United States, 1% to 4% of the population has epilepsy—i.e., two or more unprovoked seizures, and approximately…
Issues of Medical Intractability for Surgical Candidacy Patrick Kwan Martin J. Brodie INTRODUCTION Although the effectiveness of epilepsy surgery for patients with surgically remediable syndromes refractory to antiepileptic drug (AED)…
Vagus Nerve Stimulation Therapy James W. Wheless Epilepsy and seizures affect at least 2.3 million individuals in the United States (1). Although antiepileptic drugs (AEDs) are the primary form of…
The Ketogenic Diet Douglas R. Nordli Jr. Darryl C. De Vivo INTRODUCTION The ketogenic diet is a high-fat, low-carbohydrate, low-protein regimen that has been used for more than 70 years…
