Fig. 24.1 General schematic of cellular GSH biosynthesis, utilization, export, and salvage. Glutathione (GSH) biosynthesis requires two ATP-dependent reactions: the glutamate cysteine ligase (GCL)-mediated formation of γ-glutamylcysteine (γGC) from glutamate…
Fig. 5.1 Electron microscopy analysis. Mature adipocyte has thin cytoplasm and a nucleus characteristically squeezed by the large lipid vacuoles. The cytoplasmatic organelles are poorly represented. Scale bar = 4 μm To…
Fig. 13.1 2D [1H,1H] HRMAS spectra from controls (left) and GBM (right) tumor biopsies, acquired with a 600 MHz (1H) NMR spectrometer at an MAS rate of 3 kHz and…
Fig. 26.1 66-year old patient with the history of colorectal cancer who presented with vertigo and dysarthry. (a) native CT shows a dense mass in the right cerebellar hemisphere with…
Fig. 2.1 Schematic representation of adult rodent neurogenesis. (a) Illustration of a sagittal section through the mouse brain showing location of neurogenic zones: the subgranular zone (SGZ) of the dentate…
Fig. 9.1 Histology of medulloblastoma (MB) subgroups and Pie chart frequency. (a) Desmoplastic nodular MBs are composed of pale nodular areas with patterns of neuronal differentiation surrounded by densely packed…
Fig. 12.1 Time to recurrence of subsequent glioma (open bars) and meningioma (closed bars) in the Childhood Cancer Survivor Study cohort (Printed with permission from Oxford University Press (Neglia et…
Fig. 11.1 Relative risk of subsequent glioma (closed boxes) and meningioma (open boxes) within the Childhood Cancer Survivor Study cohort by radiation dose (Printed with permission from Oxford University Press,…
Fig. 27.1 Treatment planning of a left sessile HH extending into the interpeduncular cystern near the optic chiasm. This case was treated with frameless image-guided robotic radiosurgery (Cyberknife) delivering 151…
© Springer Science+Business Media Dordrecht 2014M.A. Hayat (ed.)Tumors of the Central Nervous System, Volume 12Tumors of the Central Nervous System1210.1007/978-94-007-7217-5_25 25. Drugs for Primary Brain Tumors: An Update Lauren Nye1, Timothy Huyck1 and Jeffrey Raizer2 (1) Department…
