Neupsy Key

Abstract Drugs can exert major effects on the developing central nervous system (CNS). In the broadest sense, drugs may disturb specific developmental events in the brain and, in turn, produce…

Abstract Neuromuscular disorders may cause dramatic disability in the neonatal period. The dominant features of these disorders are muscle weakness and hypotonia. In this context, we consider as neuromuscular disorders…

Abstract Seizures represent the most distinctive and frequent manifestations of neurological disease in the neonatal period. Compared with seizures in older patients, neonatal seizures have different clinical appearances, electrographic characteristics,…

Abstract Organizational events occur in a peak time period from approximately the fifth month of gestation to several years after birth. The major developmental features include (1) establishment and differentiation…

Abstract A variety of specialized studies are available for evaluating the nervous system of the newborn. In this chapter, we review several commonly used tests: cerebrospinal fluid examination, evoked responses…

Abstract There are numerous disorders of amino acid (AA) metabolism; although individually rare, they collectively are extremely important. First, they may result in devastating disturbances of neurological development, and, second,…

Abstract Space-occupying lesions—including brain tumors, vein of Galen malformations, and arachnoid cysts—represent important intracranial mass lesions and share certain clinical features. Improvements in management in recent years have made the…

Abstract Cerebellar hemorrhage is increasingly detected in both preterm and full-term newborns. This form of brain injury is more common in premature infants compared with term newborns. Cerebellar hemorrhage is…

Glucose, like oxygen, is of essential and fundamental importance for brain metabolism. Indeed, because oxygen consumption is relatively low in the neonatal human brain and minimal in such areas as…

A series of metabolic disorders with prominent neurological accompaniments and serious deleterious effects on the developing central nervous system have been described under the designation organic acid disorders . The…