Abstract The assessment of fetal well-being is a critical tool in ensuring optimal neonatal outcomes from both pregnancy and labor. This is particularly relevant for the recognition of the infant…
Abstract Intracranial hemorrhage in the neonatal period is an important clinical problem. Its importance relates to a relatively high frequency of occurrence, accompanied at times by serious neurological sequelae. Over…
Abstract Seizures represent the most distinctive and frequent manifestations of neurological disease in the neonatal period. Compared with seizures in older patients, neonatal seizures have different clinical appearances, electrographic characteristics,…
Abstract Perinatal stroke has become increasingly recognized with the increased application of neuroimaging for neonatal seizures and encephalopathy. The frequency of perinatal stroke is estimated at 1 in 5000 births….
Arthrogryposis multiplex congenita refers to a syndrome, apparent at birth, characterized by fixed positions of multiple joints and an associated limitation of movement. The term arthrogryposis is derived from the…
Abstract Cerebellar development is protracted, lasting from the fifth week of gestation until several years after birth; this exposes the cerebellum to a prolonged risk of developmental disturbance. Understanding the…
Abstract Encephalopathy of prematurity (EOP) is a histologically defined condition common in preterm infants characterized by cerebral white matter injury/periventricular leukomalacia with a variety of associated neuronal/axonal deficits. The fetal/maternal…
Abstract The major neuropathological substrate of human preterm brain injury is the encephalopathy of prematurity, a term coined to characterize the multifaceted gray and white matter lesions in the preterm…
Abstract Hypoxic-ischemic brain injury is a very important neurological problem of the perinatal period. This importance of hypoxic-ischemic brain injury relates to the general gravity of the lesions and to…
Abstract The neuropathology of the encephalopathy of prematurity (see Chapter 14 ) includes injury to cerebral white matter and, in a major proportion of infants, a variety of neuronal-axonal disturbances….
