Proliferation Markers in the Evaluation of Gliomas
CHAPTER 99 Proliferation Markers in the Evaluation of Gliomas Tarik Tihan Analysis of the cell cycle and cell proliferation is critical for the study of many biologic processes, and uncontrolled…
Approach to the Patient with Chronic Pain
CHAPTER 156 Approach to the Patient with Chronic Pain Joshua M. Rosenow Evaluating a patient with chronic pain involves multiple considerations on the part of the physician. This chapter provides…
Principles of Neurocritical Care
CHAPTER 24 Principles of Neurocritical Care Eelco F.M. Wijdicks, Alexander Y. Zubkov Medical care of a patient with an acutely deteriorating neurological or neurosurgical disorder is vastly different from that…
Adult Hydrocephalus
CHAPTER 36 Adult Hydrocephalus The Role of Endoscopic Third Ventriculostomy Jay Riva-Cambrin, James M. Drake There is little doubt that the surgical world and its accompanying literature have seen an…
Surgical Risk of Transmittable Diseases
CHAPTER 47 Surgical Risk of Transmittable Diseases Donald E. Fry The first reports of transmission of blood-borne pathogens from patients to surgeons occurred more than 50 years ago.1,2 These early…
Postoperative Infections of the Head and Brain
CHAPTER 40 Postoperative Infections of the Head and Brain Christopher J. Farrell, Mary L. Pisculli, Frederick G. Barker, II Before Lister’s 1867 introduction of surgical antisepsis, nearly 80% of operations…
Brain Tumor Outcome Studies
CHAPTER 113 Brain Tumor Outcome Studies Design and Interpretation Frederick G. Barker, II This chapter addresses issues in the design and interpretation of clinical studies in patients with brain tumors….
Principles of Chemotherapy
CHAPTER 112 Principles of Chemotherapy Karine Michaud, Susan M. Chang The first line of treatment for primary brain tumors is surgery and radiation, yet these modalities alone are rarely curative…
Production and Flow of Cerebrospinal Fluid
CHAPTER 33 Production and Flow of Cerebrospinal Fluid Conrad E. Johanson Continually generated and flowing cerebrospinal fluid (CSF) is vital for brain homeostasis.1 Day and night, the choroid plexus churns…
Pathophysiology of Subdural Hematomas
CHAPTER 37 Pathophysiology of Subdural Hematomas Brent O’Neill, Jack Wilberger, Adam Wilberger Chronic subdural hematoma (CSDH) is frequently encountered in neurosurgical practice and occurs at a rate of 1 to…
