Paraneoplastic Disorders
18 Paraneoplastic Disorders Myrna R. Rosenfeld and Josep Dalmau Introduction Paraneoplastic neurological disorders (PND) are a heterogeneous group of disorders that can affect any part of the neuraxis, including the…
Brain Metastases
13 Brain Metastases Silvia Hofer and Michael Brada Introduction Brain metastases are a common manifestation of malignancy, affecting approximately 10% of patients with solid tumors. The majority develop in the…
Neurotoxicity of Chemotherapy
16 Neurotoxicity of Chemotherapy Kate Scatchard and Siow Ming Lee Introduction Neurological side effects are a common complication following chemotherapy, and can adversely affect clinical management of the cancer patient….
Primary CNS Lymphoma
9 Primary CNS Lymphoma M. Sierra Del Rio, A. Rousseau, Carole Soussain and Hoang-Xuan Khe Introduction Primary CNS lymphomas (PCNSL) are extranodal malignant lymphomas arising within the brain, eyes, leptomeninges,…
Extraaxial Brain Tumors
11 Extraaxial Brain Tumors Nader Pouratian, Ashok R. Asthagiri, David Schiff and Jason P. Sheehan Introduction Extraaxial brain tumors (EBTs) include an array of tumors that arise from structures and…
Neurological Complications of Bone Marrow and Organ Transplantation
19 Neurological Complications of Bone Marrow and Organ Transplantation Claudio S. Padovan and Andreas Straube Introduction Organ transplantation is the only curative treatment for advanced cases of kidney, heart, liver,…
Malignant Gliomas in Adults
5 Malignant Gliomas in Adults Andrew D. Norden, Jan Drappatz and Patrick Y. Wen Introduction Malignant gliomas (MG) account for more than 75% of the approximately 20,500 newly diagnosed malignant…
Low Grade Astrocytomas
6 Low Grade Astrocytomas Lawrence D. Recht, Hannes Vogel and Griffith R. Harsh Introduction In the 1970s, 80% of nonglioblastoma gliomas were considered to be diffuse astrocytomas. The percentages of…
Medical Complications in the Management of Brain Tumors
12 Medical Complications in the Management of Brain Tumors Robin Grant Introduction Patients with brain tumors present with neurological symptoms in a variety of different ways, usually either to their…
Clinical Features of Brain Tumors
3 Clinical Features of Brain Tumors Lakshmi Nayak and Lisa M. Deangelis Introduction The symptoms and signs of a brain tumor resemble those seen in other focal neurological diseases, but…
