Principles of Blood Loss
7 Principles of Blood Loss Tsinsue Chen, Rami O. Almefty, and Peter Nakaji Blood loss, a universal concern in surgery, is only somewhat mitigated by the possibility of blood replacement…
Pediatric Neurosurgery–Specific Patient/Case Examples
29 Pediatric Neurosurgery–Specific Patient/Case Examples Mark G. Hamilton and John R.W. Kestle Anticoagulation management is not typically an important aspect of pediatric neurosurgical care. However, pediatric patients face significant risk…
Cranial Venous Sinus Thrombosis Diagnosis and Management
13 Cranial Venous Sinus Thrombosis Diagnosis and Management Andrew Demchuk and Jose Andres Venegas-Torres Cerebral venous sinus thrombosis (CVST), or thrombosis of the intracranial veins and sinuses, is a rare…
Specific Anticoagulant and Antiplatelet Agent Reversal Strategies for Neurosurgical Patients
14 Specific Anticoagulant and Antiplatelet Agent Reversal Strategies for Neurosurgical Patients Shahid M. Nimjee and Gerald A. Grant In 1916, a medical student named Jay Mclean stumbled across a substance…
Risk of Anticoagulants and Antiplatelet Agents in Trauma Patients
23 Risk of Anticoagulants and Antiplatelet Agents in Trauma Patients Michael C. Huang, Mathieu Laroche, and Geoffrey T. Manley Trauma is the leading cause of death and disability in children,…
The Role of Evidence-Based Medicine in Bleeding and Coagulation Management in the Neurosurgical Patient
1 The Role of Evidence-Based Medicine in Bleeding and Coagulation Management in the Neurosurgical Patient Alexander A. Leung and William A. Ghali Evidence-based medicine (EBM) has been widely promoted as…
Herbal Products and Supplements Affecting Coagulation
6 Herbal Products and Supplements Affecting Coagulation Omar Tanweer, Shaun David Rodgers, and John G. Golfinos A neurosurgical procedure may be meticulously planned for hemostasis preoperatively, intraoperatively, and postoperatively. But…
Clinical Disorders of Coagulation and Platelet Function
4 Clinical Disorders of Coagulation and Platelet Function Justin D. Thomas and George M. Rodgers This chapter briefly summarizes disorders of bleeding and thrombosis, including both inherited and acquired etiologies….
Intraoperative Non-Hematologic Adjuvant Methods for Preventing Blood Loss
17 Intraoperative Non-Hematologic Adjuvant Methods for Preventing Blood Loss Ian Y. Lee, Raymond Sawaya, and Nicholas B. Levine Hemostatic techniques, including metal clips, mechanical tamponade, and ligature, used in other…
Drugs Affecting Coagulation and Platelet Function
5 Drugs Affecting Coagulation and Platelet Function Amir Assel and Kenneth B. Hymes The management of bleeding in the perioperative setting is important to any surgeon, and the use of…
