Type of presurgical deficit Laterality findings Change with surgery Language functions Naming (auditory/visual) Both left and right TLE—frequently exhibit deficits (left > right) Left TLE—decline Right TLE—no decline Semantic fluency Both left…
© Springer Science+Business Media New York 2015William B. Barr and Chris Morrison (eds.)Handbook on the Neuropsychology of EpilepsyClinical Handbooks in Neuropsychology10.1007/978-0-387-92826-5_12 12. Evaluation and Management of Psychogenic Nonepileptic Attacks John T. Langfitt1, 2 and William Watson3 (1) Departments…
Fig. 1 Pre-surgical MRI to determine surgical coordinates. (a) Animals are anesthetized and fitted into an MRI-compatible stereotaxic head frame by first securing the animal into the ear bars, followed…
Cell number Amount of media for culture Amount of media for a virus infection 1 6 well 1.1 × 106 in one well 2 mL 1 mL 2 T25 3 × 106 4…
Fig. 1 Transduction of neurons and glia in the myenteric plexus of the ENS. Adult male rats received direct injection s of AAV9 (a–d) or AAV6 (e–h) expressing green fluorescent…
Fig. 1 Skull surface sutures and reference points. Stereotaxic surgery utilizes reference points created by the intersection of skull sutures to pinpoint the location of neuroanatomical structures in the brain…
Fig. 1 Diffusion-based delivery results in a limited area of distribution and reflux along the needle track. Increased flow rate with CED results in a pressurized extracellular bulk flow that…
Fig. 1 Time-course analysis of early GL26-Cit glioma growth in the striatum in mice. To visualize perivascular glioma growth GL26-Cit cells were implanted in RA/EGxdelCre mice that express GFP in…
Fig. 1 rAAV2/5 efficiently transduces neurons and produces equal protein expression in the young and aged rat hippocampus (HP). (a–d) Young adult (a and c, 6 months, n = 3) and old…
Model Construct Validity? Reproducible? Progressive nigrostriatal degeneration? Parkinsonian pathology? Parkinsonian symptoms? References Construct validity for idiopathic PD Within group Across groups Striatal DA terminal dysfunction/loss (over weeks) Terminal loss precedes…
