Rat Mutants with Lateralized Rotational Behavior for Studying Disturbances in Cerebral Asymmetries and Their Involvement in Brain Disorders

Apr 2, 2017 by in NEUROSURGERY Comments Off on Rat Mutants with Lateralized Rotational Behavior for Studying Disturbances in Cerebral Asymmetries and Their Involvement in Brain Disorders

Fig. 3.1. Lateralized circling behavior of ci2/ci2 and ci3/ci3 rats. All data are shown as means  ±  SEM. (a) illustrates the average number of rotations of 88 ci2/ci2 rats in…

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Knockout and Mutant Rats

Apr 2, 2017 by in NEUROSURGERY Comments Off on Knockout and Mutant Rats

Fig. 2.1. Social play behavior in periadolescent (aged between 28 and 35 days) rats. SERT−/− rats played significantly less compared to SERT+/+ rats. Social aggression has also been studied in…

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Investigating Rett Syndrome Through Genetic Mouse Models: Presymptomatic, Clearly Symptomatic Phases, and Innovative Therapeutic Approaches

Apr 2, 2017 by in NEUROSURGERY Comments Off on Investigating Rett Syndrome Through Genetic Mouse Models: Presymptomatic, Clearly Symptomatic Phases, and Innovative Therapeutic Approaches

In the MeCP2Bird model (18), male and female mice appeared normal till the third postnatal week, afterward both sexes developed gross abnormalities (with sex-dimorphic time course) consisting of a stiff,…

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Chronic Pain Stimuli Downregulate Mesolimbic Dopaminergic Transmission: Possible Mechanism of the Suppression of Opioid Reward

Apr 2, 2017 by in NEUROSURGERY Comments Off on Chronic Pain Stimuli Downregulate Mesolimbic Dopaminergic Transmission: Possible Mechanism of the Suppression of Opioid Reward

, Keiichi Niikura2, Akira Yamashita2, Daigo Ikegami2, Naoko Kuzumaki2, Michiko Narita2 and Tsutomu Suzuki3 (1) Life Science Tokyo Advanced Research Center (L-StaR), 2-4-41 Ebara, Shinagawa-ku, Tokyo 142-8501, Japan (2) Department of Pharmacology, Hoshi University School of Pharmacy…

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Opioid Self-Administration in the Presence of Chronic Pain: Analgesia or Addiction?

Apr 2, 2017 by in NEUROSURGERY Comments Off on Opioid Self-Administration in the Presence of Chronic Pain: Analgesia or Addiction?

© Springer Science+Business Media New York 2014Carolyn A. Fairbanks and Thomas J. Martin, Ph.D. (eds.)Neurobiological Studies of Addiction in Chronic Pain StatesContemporary Clinical Neuroscience1710.1007/978-1-4939-1856-0_2 2. Opioid Self-Administration in the Presence of Chronic Pain: Analgesia or…

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Opioids in an Evidence-Based World

Apr 2, 2017 by in NEUROSURGERY Comments Off on Opioids in an Evidence-Based World

© Springer Science+Business Media New York 2014Carolyn A. Fairbanks and Thomas J. Martin, Ph.D. (eds.)Neurobiological Studies of Addiction in Chronic Pain StatesContemporary Clinical Neuroscience1710.1007/978-1-4939-1856-0_8 8. Opioids in an Evidence-Based World Scott A. Strassels1   (1) Department of Health…

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