Fig. 1.1 Schematic representation of defined loci and genes for PD, including Mendelian genes and loci identified by association studies. The loci, gene symbols, and chromosomal position are indicated. EO-PD…
SNP ID Locus name Chromosome (bp) Odds ratio rs35749011 GBA/SYT11 1 (155,135,036) 1.824 rs114138760a GBA/SYT12 1 (154,898,185) 1.519 rs823118 RAB7L1/NUCKS1 1 (205,723,572) 1.122 rs10797576 SIPA1L2 1 (232,664,611) 1.131 rs6430538 ACMSD/TMEM163…
Fig. 4.1 Evolution of IA therapy trials over time. More positive trials with newer devices and technology over time. Positive trials: Circles at the upper border, Negative trials: Circle at…
Direct blow to the head and neck Chiropractic neck manipulation Strangulation Atlanto-axial sublaxation Elongated styloid process Cervical spine fracture Basal skull fracture Excessive head banging Beauty parlor syndrome Labor and…
Fig. 8.1 An 83-year-old man without any vascular risk factors developed dysarthria and confusion. DWI showed multiple scattered infarcts in bilateral anterior and posterior circulations. MR angiography, electrocardiography and echocardiography…
Age decade Silent brain infarcts (%) Microbleeds (%) 40–49 1–5 2 50–59 3–8 2–3 60–69 8–15 5–18 70–79 12–20 8–31 80+ 20–35 10–38 Prevalence data are from community- and population-based…
Fig. 3.1 Multimodal CT imaging of acute ischemic stroke patient presenting at 4 h of symptom onset, baseline non-contrast CT scan shows early changes of ischemia in the left insula…
Fig. 12.1 Valve prostheses. Different prosthetic heart valves. Bioprosthetic valve (top left). Prosthetic bileaflet (top middle and bottom left). Ball in cage prosthesis (middle right). Annuloplasty ring (bottom right). By…
Element/stroke center type Acute stroke ready Primary stroke center Comprehensive stroke centers Setting Rural/small urban Suburban, urban Large urban Size (beds) <100 100–500 >500 Stroke patient volume (year) 20–70 100–600…
Fig. 23.1 Basic principles of transcranial magnetic stimulation. The magnetic coil, represented as a figure-of-eight device, is placed on top of the cerebral cortex and pulses a magnetic field that…
