14 Nucleus Replacement and Repair: Autologous Disc Chondrocyte Transplantation Christian Hohaus, Timothy Ganey, and Hans Jörg Meisel Abstract Intervertebral disc (IVD) degeneration is in 40% of younger individuals and in more…
Fig. 2.1 Degenerative disc disease is a complicated process with many factors interacting to lead to the disc pathology that presents in the clinic. This figure demonstrates many of those…
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16 Summary of Clinical Trials with Biological Treatment Approaches for Spinal Disease Gernot Lang, Ibrahim Hussain, Micaella Zubkov, Yu Moriguchi, Brenton Pennicooke, Rodrigo Navarro-Ramirez, and Roger Härtl Abstract Biological-based treatment approaches…
8 Intervertebral Disc Whole Organ Cultures Marianna Peroglio, Zhen Li, Lorin Michael Benneker, Mauro Alini, and Sibylle Grad Abstract Whole intervertebral disc (IVD) organ cultures bridge the gap between in vitro…
4 Biomechanics of the Healthy and Diseased Spine Hans-Joachim Wilke and Fabio Galbusera Abstract The intervertebral disc (IVD) is a pad of soft tissue that uniformly distributes the stresses due to…
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