Acquired Presynaptic Neuromuscular Junction Disorders: Infant Botulism and Lambert-Eaton Myasthenic Syndrome

Jun 25, 2019 by in NEUROLOGY Comments Off on Acquired Presynaptic Neuromuscular Junction Disorders: Infant Botulism and Lambert-Eaton Myasthenic Syndrome

Keywords Infantile botulism, Lambert-Eaton myasthenic syndrome, LEMS, neuromuscular transmission disorders, myasthenia, myopathy   Infant Botulism Botulism is derived from the Latin botulus , for sausage. Van Ermengem in 1897 isolated…

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Neuropathies Secondary to Systemic Disorders

Jun 25, 2019 by in NEUROLOGY Comments Off on Neuropathies Secondary to Systemic Disorders

Keywords Systemic disease, renal failure, diabetes mellitus, critical illness polyneuropathy, paraneoplastic, vitamin deficiencies, connective tissue diseases   Introduction There is a clear distinction between a peripheral neuropathy that is clinically…

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Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Jun 25, 2019 by in NEUROLOGY Comments Off on Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Keywords CIDP, peripheral nerve, inherited neuropathies, electrodiagnosis, IVIg, plasma exchange   Epidemiology Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) comprises a small but important subset of chronic childhood polyneuropathies. One series identified…

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Hansen’s Disease (Leprosy): Leprous Neuropathy

Jun 25, 2019 by in NEUROLOGY Comments Off on Hansen’s Disease (Leprosy): Leprous Neuropathy

Keywords Leprosy, leprosy diagnosis, leprosy neuropathy, leprosy reaction, leprosy neuritis   Introduction Leprosy is a chronic infectious disease caused by Mycobacterium leprae ( M. leprae ), an acid-fast, Gram-positive, rod-shaped,…

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Toxic Neuropathies

Jun 25, 2019 by in NEUROLOGY Comments Off on Toxic Neuropathies

Keywords Toxic neuropathy, cisplatin, vincristine, paclitaxel, chloroquine, metronidazole, nitrofurantoin, colchicine, thalidomide, pyridoxine, hexane, organophosphates, thallium, arsenic, buckthorn   Introduction In a sense, all peripheral nervous system (PNS) disorders caused by…

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Acute Polyneuropathies

Jun 25, 2019 by in NEUROLOGY Comments Off on Acute Polyneuropathies

Keywords Guillain-Barré syndrome, flaccid paralysis, demyelinating, axonal, neuropathy, pediatric, tick paralysis   Introduction The acute polyneuropathies are a group of acquired, generally immune-mediated or infectious disorders causing dysfunction and sometimes…

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Peripheral Neuropathy in Inherited Metabolic Disease

Jun 25, 2019 by in NEUROLOGY Comments Off on Peripheral Neuropathy in Inherited Metabolic Disease

Keywords Inherited metabolic diseases, sphingolipidoses, glycoproteinoses, amino acids, fatty acids, mitochondrial diseases, peroxisomal diseases, lipids, glycogen storage diseases, Leigh disease   Introduction Peripheral neuropathy is associated with numerous inherited metabolic…

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Congenital and Early Infantile Neuropathies

Jun 25, 2019 by in NEUROLOGY Comments Off on Congenital and Early Infantile Neuropathies

Keywords Pediatric, infantile, peripheral neuropathy, demyelination, axonal, Charcot-Marie-Tooth disease, Dejerine-Sottas disease, congenital hypomyelinating neuropathy   Introduction The congenital and infantile neuropathies are an uncommon and complex group of conditions with…

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Mononeuropathies

Jun 25, 2019 by in NEUROLOGY Comments Off on Mononeuropathies

Keywords Neuropathy, mononeuropathy, pediatric, median, ulnar, peroneal, tibial, sciatic   Introduction Mononeuropathies are rare in children, accounting for fewer than 10% of pediatric referrals for electromyographic (EMG) testing. This is…

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Overview of Pediatric Peripheral Neuropathies

Jun 25, 2019 by in NEUROLOGY Comments Off on Overview of Pediatric Peripheral Neuropathies

Keywords Peripheral neuropathy, Charcot-Marie-Tooth disease, Guillain-Barré syndrome, electromyography   Introduction The term peripheral neuropathy refers to a disorder affecting one or more components of the peripheral nervous system, specifically axons,…

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