Pituitary Tumors
10.1055/b-0034-79108 Pituitary TumorsErin N. Kiehna, Edward R. Laws Jr., and John A. Jane Jr. Pituitary tumors are relatively uncommon pediatric brain tumors, accounting for only 2 to 6% of tumors…
Supratentorial Primitive Neuroectodermal Tumors
10.1055/b-0034-79107 Supratentorial Primitive Neuroectodermal TumorsSunil Bhat, Verity Ann Ahern, and Stewart J. Kellie Primitive neuroectodermal tumors (PNETs) of the central nervous system (CNS) are a diverse group of malignant embryonal…
Craniopharyngiomas
10.1055/b-0034-79106 CraniopharyngiomasJeffrey H. Wisoff and Robert E. Elliott Craniopharyngiomas constitute approximately 3% of all intracranial neoplasms.1,2 They are the most common nonglial tumor of childhood, accounting for 6 to 9%…
Convection-Enhanced Delivery
10.1055/b-0034-79100 Convection-Enhanced DeliveryGautam U. Mehta and Russell R. Lonser As many as 15 to 20% of pediatric central nervous system (CNS) tumors are located in the brainstem.1 These tumors, particularly…
Supratentorial Astrocytomas
10.1055/b-0034-79103 Supratentorial AstrocytomasIan F. Pollack Historical Context Gliomas account for the majority of supratentorial tumors in childhood.1 In contrast to the situation in adults, low-grade gliomas are substantially more common…
Radiation Therapy for Pediatric CNS Malignancies
10.1055/b-0034-79098 Radiation Therapy for Pediatric CNS MalignanciesShannon M. MacDonald and Nancy J. Tarbell Pediatric central nervous system (CNS) malignancies represent the most common solid malignancy of childhood and account for…
Supratentorial Ependymomas
10.1055/b-0034-79105 Supratentorial EpendymomasMichael DeCuypere, Paul Klimo Jr., Robert A. Sanford, and Frederick A. Boop Tumors of the ependyma are the third most prevalent primary brain malignancy in children, after astrocytomas…
Stereotactic Radiosurgery
10.1055/b-0034-79099 Stereotactic RadiosurgeryAmanda L. Yaun Decades of experience have proven stereotactic radiosurgery to be an effective means of local tumor control in carefully selected patients. Studies specific to the pediatric…
Gene Therapy for Pediatric Brain Tumors
10.1055/b-0034-79102 Gene Therapy for Pediatric Brain TumorsKaveh Asadi-Moghaddam, E. Antonio Chiocca, David W. Pincus, and Corey Raffel In recent years, important progress has been made in understanding the molecular bases…
Inheritable Genetic Variations Predisposing to CNS Tumors
10.1055/b-0034-79094 Inheritable Genetic Variations Predisposing to CNS TumorsJonathan L. Finlay and Uri Tabori Cancer is a genetic disease. However, not all cancers are inherited, and although some genetic variations predisposing…
