Chapter 8 Current Surgical Management of High-Grade Gliomas Ray M. Chu, Keith L. Black The malignant glioma has been the neurosurgeon’s eternal hydra, continually growing despite treatment. The category “high-grade…
Chapter 48 Surgical Management of Neurofibromatosis Types 1 and 2 James H. Tonsgard, Bakhtiar Yamini, David M. Frim Neurofibromatosis types 1 and 2 (NF1 and NF2) are genetic diseases that…
Chapter 18 Growth Hormone–Secreting Tumors Carrie R. Muh, Adriana G. Ioachimescu, Nelson M. Oyesiku Hypersecretion of growth hormone (GH) from a functioning pituitary tumor before the closure of the epiphyseal…
Chapter 3 Functional Tractography, Diffusion Tensor Imaging, Intraoperative Integration of Modalities, and Neuronavigation Jonathan A. Hyam, Alexander L. Green, Erlick A.C. Pereira Diffusion tensor imaging (DTI) with functional tractography is…
Chapter 19 Prolactinomas James K. Liu, Mark D. Krieger, Arun P. Amar, William T. Couldwell, Martin H. Weiss Prolactinomas are the most common type of functioning pituitary tumors, accounting for…
Chapter 6 Cortical and Subcortical Brain Mapping Hugues Duffau The first goal of brain surgery, especially in neuro-oncology, is to optimize the extent of resection (EOR) of the lesion. Indeed,…
Chapter 14 Cerebellar Tumors in Adults Laura B. Ngwenya, Mirza N. Baig, Manish K. Aghi, E. Antonio Chiocca Many lesions affect the posterior fossa, and the cerebellum in particular. Some…
Chapter 16 Multimodal Assessment of Pituitary and Parasellar Lesions T. Brooks Vaughan, Lewis S. Blevins, Michael S. Vaphiades, Gary S. Wand Pituitary and parasellar lesions represent a unique variety of…
Chapter 7 Chemotherapy for Brain Tumors Manmeet S. Ahluwalia Factors Influencing Delivery of Chemotherapy to the Brain Blood–Brain Barrier Treatment of brain tumors with systemic chemotherapy poses challenges unique to…
Secondary to breakdown of blood-brain barrier, leakage of (normally excluded) intravascular proteins and fluid into the cerebral interstitial space. Primarily affects white matter. Seen around tumours, abscesses. Can occur in…
