Radiation Treatment for Chordomas
Chordomas are rare tumors that arise from remnants of the notochord. They are encountered in the skull base and upper cervical spine or in the sacrum. Skull base chordomas are…
The Descriptive Epidemiology of Chordomas
Chordoma is a rare bony tumor, afflicting approximately 300 persons a year in the United States. 1 These lesions are thought to arise from transformed remnants of the fetal notochord…
Cytogenetics of Chordomas
Chordomas are a rare tumor, thought to arise from neoplastic transformation of embryonic notochordal rests. 1 The genetic and molecular mechanisms underlying the development of chordoma are not well understood….
Molecular Imaging of Chordomas
Computed tomography (CT) and magnetic resonance imaging (MRI) provide exquisite anatomical detail that can help to differentiate chordoma from other tumors, as discussed in Chapter 10. The strength of molecular…