Dopamine Transporter Imaging
Fig. 11.1 Nigrostriatal dopaminergic synapse and targets of PET and SPECT ligands. Tyrosine is converted to L-DOPA by tyrosine hydroxylase. L-DOPA is then converted to dopamine, which is gathered into…
Fig. 11.1 Nigrostriatal dopaminergic synapse and targets of PET and SPECT ligands. Tyrosine is converted to L-DOPA by tyrosine hydroxylase. L-DOPA is then converted to dopamine, which is gathered into…
Fig. 1.1 Typical brain stem-type Lewy body (upper) and cortical Lewy body (lower) and the distribution of Lewy bodies in our first case Fig. 1.2 Alpha-synuclein-immunostained Lewy bodies in the…
Diffuse Lewy body disease (DLBD) Kosaka et al. [1], Dickson et al. [2], Lennox et al. [3] Lewy body dementia (LBD) Gibb et al. [4] Lewy body variant of Alzheimer’s…
Fig. 6.1 Differentiation between DLB and AD DLB by using neuropsychological tests. (a) ADAS word recall score and WAIS-R blocks design score. (b) Total MMSE score and MMSE calculation/attention score…
Rest tremor Freezing Rigidity Freezing Bradykinesia Festination Reptile stare Abnormal posture Masked face Camptocormia Small voice Pisa syndrome Dysphagia Head drop Bradykinesia Loss of automatic acts Micrographia Drooling Shuffling gait…
© Springer Japan KK 2017Kenji Kosaka (ed.)Dementia with Lewy Bodies10.1007/978-4-431-55948-1_3 3. Cholinergic Pathology in Dementia with Lewy Bodies John-Paul Taylor1 , Daniel Collerton1, Fiona LeBeau1 and Elaine Perry1 (1) Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, NE4 5PL,…
© Springer Japan KK 2017Kenji Kosaka (ed.)Dementia with Lewy Bodies10.1007/978-4-431-55948-1_7 7. Behavioral and Psychological Symptoms of Dementia Yuta Manabe1, 2, 3 and Kenji Kosaka3, 4 (1) Dementia Diagnostic Center, Yokohama Shintoshi Neurosurgery Hospital, 433, Eda-chou, Aoba-ku,…
Study No. in study Age (years) No. with dementia No. of DLB DLB/over 65 years, % (95 %CI) DLB/all dementia, % (95 %CI) Yamada (2001) 3715 65 142 4 0.11 (0.03–0.28) 0.28…
and Uwe Spetzger1 (1) Department of Neurosurgery, Klinikum Karlsruhe, Karlsruhe, Baden-Württemberg, Germany The anterior standard approach is the most frequently used surgical approach to the cervical spine. It is suitable…
and Uwe Spetzger1 (1) Department of Neurosurgery, Klinikum Karlsruhe, Karlsruhe, Baden-Württemberg, Germany For younger patients with soft-disc herniation, only slight osteochondrosis, and good range of motion in the affected level…