Fig. 29.1 Coagulation cascade with commonly used anticoagulants and their antidotes. FFP fresh frozen plasma, PCC prothrombin complex concentrates 29.1 Anticoagulant Agents 29.1.1 Warfarin Warfarin, also known as Coumadin, is…
Fig. 28.1 Mechanisms of antiplatelet drugs 28.1 Antiplatelet Therapy of Acute Ischemic Stroke and TIA 28.1.1 Aspirin vs. Placebo In the International Stroke Trial (IST), patients received aspirin 300 mg…
Fig. 7.1 The history of thrombolysis. Prolyse in Acute Cerebral Thromboembolism (PROACT) II trial; The Mechanical Embolus Removal in Cerebral Ischemia (MERCI); Interventional Management of Stroke [IMS] III; Local Versus…
Patient care elements Acute stroke team Written care protocols Emergency medical services Emergency department Stroke unit Neurosurgical services Imaging services: brain, cerebral vasculature, cardiac Laboratory services Rehabilitation services Administrative/support elements…
Fig. 2.1 Stroke unit. Interior view of stroke unit (a); exterior (b) and interior (c) view of mobile stroke unit. Reproduced by permission of Business Wire (University of Tennessee Web…
Fig. 6.1 History of clinical trials of IV thrombolysis Finally, following the publication of the ECASS-III study in 2008, the time window for administration of intravenous (IV) thrombolysis was expanded…
Fig. 4.1 A schematic diagram showing patient management flow (CT computed tomography, MRI magnetic resonance imaging, IV intravenous, IA intra-arterial) 4.1 Care in the Emergency Unit Treatment of suspected stroke…
Fig. 1.1 Hand motor fMRI activation in a patient with two contrast enhancing tumors that both displace the motor gyrus and efface the central sulcus. The red line indicates the position…
Fig. 6.1 Scheme illustrating the nature of fluorescence and how it is visualized A Brief History Historically, the use of a fluorophore for highlighting malignant glioma tissue was first described by…
Fig. 7.1 MRI-compatible surgical suite at Yale New Haven Hospital. Patient positioning and preparation prior to obtaining pre-LITT MRI. Heat delivery is performed under MRI guidance for intra-procedural monitoring and confirmation…
