Fig. 1 Flow cytometric staining of the inflammatory infiltrate at the peak of EAE. (a) CD4 versus CD11b staining of CNS cells (initially gated using a live leukocyte gate). (b)…
Fig. 1 Immunohistochemistry, confocal fluorescence microscopy, and in situ hybridization techniques. (a, b, c, bar: 1 cm) Hemispheric sections from the brain of an RRMS patient. (a) Luxol Fast Blue/periodic acid…
Straina Haplotype Class I Class II Class III Class I RT1.A RT1.B RT1.D RT1.C DA av1 a a a av1 av1 COP av1 a a a av1 av1 ACI av1…
Fig. 1 Time schedule for oocyte production and retransfer First injection: 200 μl GnRH analog i.p. at 9 a.m. on day −5. Second injection: 300 μl PMSG i.p. at 1 p.m. on day −3….
Fig. 1 Representative immunofluorescence images of myelinating cultures (28 DIV). (a) Two colour immunofluorescence microscopy reveals the presence of a dense bed of neurites (Red; neurofilament-specific antibody SMI31) and myelinating…
Fig. 1 Schematic illustration of the electrochemiluminescence NfL immunoassay. The carbon ink electrodes are coated with the capture mAB 47:3. The biotinylated detection mAB 2:1 binds to SULFO-TAG labelled streptavidin,…
Fig. 1 Principle of ELISPOT. For cytokine ELISPOT assay, the membrane of an ELISPOT plate is coated first with capture antibody as shown in (a). (b) Cytokines that are produced…
Fig. 1 Isolation of CNS infiltrating cells from C57Bl/6 mice with EAE. (a) Absolute numbers of live and CD90 positive cells. Data represents CNS isolated material from 19 EAE diseased…
Fig. 1 cEEG demonstrating NCSE only detected with depth electrodes (D leads) in a 59-year-old woman with refractory status epilepticus despite pentobarbital, midazolam, levetiracetam, valproate, and phenytoin. Note the relative…
Fig. 1 Extreme delta brush pattern (arrow) and seizure onset in a patient with NMDA encephalitis Patients with antibodies to the leucine-rich glioma-inactivated 1 (LGI1) protein component of the voltage-gated…
