Assessing the economic costs of parental mental illness
where B = benefits (such as QALYs or depression-free days), C = costs, int = intervention group, comp = comparator group. Within the healthcare sector, the tools of economic evaluation…
Cognitive remediation for major depressive disorder
Figure 21.1 Number of minutes of online homework on a computerized cognitive training program, as a function of treatment response status (defined as magnitude of change in cognitive ability). Each…
Subjective measures of cognitive dysfunction in major depressive disorder
Figure 17.1 Percentage of subjects with clinically significant cognitive complaints based on the BC-CCI. Adapted from Iverson & Lam (2013). Cognitive symptoms also clearly affect psychosocial functioning. Sad mood and…
Insulin resistance and implications for hippocampal volume/function and the default mode network
Figure 15.1 Scatterplot between HOMA-IR and right hippocampal volume corrected for total brain volume (Rasgon et al., 2011). Results also indicated significant associations between higher HOMA-IR and reduced scores on…
Inflammation and cognition in major depressive disorder
Figure 12.1 A phase-specific neuroimmune model of clinical depression with remission. Legend: This figure represents an acute clinical depressive episode with full remission in the context of the three phases…
Measuring the mind: detecting cognitive deficits and measuring cognitive change in patients with depression
Figure 16.1 Cognitive tests and their associated domains identified by Lee et al. (2012). Legend: CVLT-II, California Verbal Learning Test 2nd Edition; HVLT, Hopkins Verbal Learning Test; ID/ED, Intradimensional/Extradimensional; LD,…
A novel treatment targeting cognitive dysfunction in mood disorders
Figure 20.1 (a): The percentage improvement from individual baseline in a memory composite score (the original figure and a description of how the composite score was calculated can be found…
Exercise and cognition
html xmlns=”http://www.w3.org/1999/xhtml” xmlns:mml=”http://www.w3.org/1998/Math/MathML” xmlns:epub=”http://www.idpf.org/2007/ops”> 22 Exercise and cognition Guy Faulkner, Markus J. Duncan, and Mehala Subramaniapillai Introduction The possibility that exercise could be used as a treatment in mental illness…
Treatment of cognitive dysfunction in adults with major depressive disorder
Figure 19.1 Standardized effect size (Cohen’s d) of vortioxetine (10 mg and 20 mg) on objective neuropsychological measures (McIntyre et al., 2014). Several lines of evidence indicate that subjective measures…
Neuroscience of functional outcomes and treatment targets in major depressive disorder
html xmlns=”http://www.w3.org/1999/xhtml” xmlns:mml=”http://www.w3.org/1998/Math/MathML” xmlns:epub=”http://www.idpf.org/2007/ops”> 18 Neuroscience of functional outcomes and treatment targets in major depressive disorder Lisanne M. Jenkins, Amy Peters, Rachel H. Jacobs, and Scott A. Langenecker Research is…
