Figure 12.1 A phase-specific neuroimmune model of clinical depression with remission. Legend: This figure represents an acute clinical depressive episode with full remission in the context of the three phases…
Figure 16.1 Cognitive tests and their associated domains identified by Lee et al. (2012). Legend: CVLT-II, California Verbal Learning Test 2nd Edition; HVLT, Hopkins Verbal Learning Test; ID/ED, Intradimensional/Extradimensional; LD,…
Figure 20.1 (a): The percentage improvement from individual baseline in a memory composite score (the original figure and a description of how the composite score was calculated can be found…
html xmlns=”http://www.w3.org/1999/xhtml” xmlns:mml=”http://www.w3.org/1998/Math/MathML” xmlns:epub=”http://www.idpf.org/2007/ops”> 22 Exercise and cognition Guy Faulkner, Markus J. Duncan, and Mehala Subramaniapillai Introduction The possibility that exercise could be used as a treatment in mental illness…
Figure 19.1 Standardized effect size (Cohen’s d) of vortioxetine (10 mg and 20 mg) on objective neuropsychological measures (McIntyre et al., 2014). Several lines of evidence indicate that subjective measures…
html xmlns=”http://www.w3.org/1999/xhtml” xmlns:mml=”http://www.w3.org/1998/Math/MathML” xmlns:epub=”http://www.idpf.org/2007/ops”> 18 Neuroscience of functional outcomes and treatment targets in major depressive disorder Lisanne M. Jenkins, Amy Peters, Rachel H. Jacobs, and Scott A. Langenecker Research is…
html xmlns=”http://www.w3.org/1999/xhtml” xmlns:mml=”http://www.w3.org/1998/Math/MathML” xmlns:epub=”http://www.idpf.org/2007/ops”> 14 White matter neurobiology and cognitive dysfunction in major depressive disorder Geoffrey Chern-Yee Tan and Kang Sim Introduction Major depressive disorder (MDD) is an affective disorder…
Figure 6.1 The impact of depression on cold cognitive function. Pooled, weighted Cohen’s d effect sizes reflecting the performance of currently depressed patients (black bars) and remitted depressed patients (gray…
Figure 13.1 A simplified diagram depicting the HPA axis and its feedback mechanism. Glucocorticoids, principally cortisol in humans, influence the expression of genes comprising approximately a fifth of the genome…
Figure 11.1 Neuropsychological model of depression. Adapted from Roiser et al. (2012), with permission. Cognitive deficits and the role of antidepressant treatment A review of antidepressant treatment effects on cognitive…
