html xmlns=”http://www.w3.org/1999/xhtml” xmlns:mml=”http://www.w3.org/1998/Math/MathML” xmlns:epub=”http://www.idpf.org/2007/ops”> Chapter 9 Frontotemporal dementia Shirley Y. Pang and Bruce L. Miller The Behavioral Neurology of Dementia, 2nd edn, ed. Bruce Miller and Bradley Boeve. Published by…
Figure 8.1 Protein and functional imaging in Alzheimer’s disease. (A) Pittsburgh compound B (PIB) binds to brain amyloid in a patient clinically diagnosed with Alzheimer’s disease (AD) compared with a…
Fig. 16.1 Schematic of experimental design. Shown are the steps using phMRI to identify common brain activity in drugs at risk, and those for treating suicidal ideation and self-harm. Finding the…
Fig. 3.1 Regulatory history and perspectives on SIB assessment. a 1991–2008 b 2009–2013 European Regulators were the first to post restrictions on the use of antidepressants. In 2003, the UK Medicines…
Fig. 2.1 Public health burden of suicidal behavior among adults aged ≥18 years—United States, 2008 (Source Crosby et al. 2011). *Source CDC’s National Vital Statistics System. All rates per 100,000 population. § Agency…
Validity Description Challenges Face The animal model should recapitulate one or more of the core symptoms of the disease Difficult to replicate the features of suicide in a non-human species…
Fig. 4.1 Suicidal ideation and behavior categories and definitions (FDA 2012) Suicidal ideation and a history of suicidal behavior are among the most salient short- and long-term risk factors for suicide…
Fig. 17.1 miRNA biogenesis. miRNAs are encoded in the genome (inter or intragenis) and transcribed by RNA polymerase II to generate primary microRNA (pri-miRNA). These pri-miRNAs are taken up by Drosha/DGCR8,…
© Springer International Publishing Switzerland 2014Keri E. Cannon and Thomas J. Hudzik (eds.)Suicide: Phenomenology and Neurobiology10.1007/978-3-319-09964-4_15 15. Human Imaging Studies of Suicidal Behavior and its Risk Factors Kees van Heeringen1 , Stefanie Desmyter1 and Stijn Bijttebier1 (1) Unit for Suicide…
© Springer International Publishing Switzerland 2014Keri E. Cannon and Thomas J. Hudzik (eds.)Suicide: Phenomenology and Neurobiology10.1007/978-3-319-09964-4_14 14. Cognitive Therapy with Suicidal Patients Michael E. Thase1 (1) Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania and…
