Second-Generation Antiepileptic Drugs
27 CHAPTER Second-Generation Antiepileptic Drugs Kathryn Idol Xixis, Roha Khalid, and Mohamad A. Mikati In 1993, a new era in antiepileptic drug (AED) treatment commenced. After a hiatus of almost…
Neuropsychological Evaluation
23 CHAPTER Neuropsychological Evaluation Phillip D. Ruppert and Sarah E. Cook In the United States, there are approximately 200,000 new epilepsy diagnoses made each year, and approximately 3 million Americans…
Epileptic Seizures
3 CHAPTER Epileptic Seizures Matthew W. Luedke and Rodney A. Radtke Recent advances in epilepsy and neurophysiology have naturally made the field more complex. As video electroencephalography (vEEG), continuous EEG…
Third-Generation Antiepileptic Drugs
28 CHAPTER Third-Generation Antiepileptic Drugs Cesar C. Santos The U.S. Food and Drug Administration (FDA) approved the third-generation antiepileptic drugs (AEDs) between 2004 and 2012. The AEDs included in this…
Status Epilepticus and Frequent Nonconvulsive Seizures
34 CHAPTER Status Epilepticus and Frequent Nonconvulsive Seizures Keith E. Dombrowski Status epilepticus (SE), particularly generalized convulsive status epilepticus (GCSE), is a common problem encountered in the United States and…
Ambulatory EEG
13 CHAPTER Ambulatory EEG Robbie D. Buechler Ambulatory electroencephalography (AEEG) is a monitoring technique that allows the recording of continuous EEG (cEEG) activity when patients are at home. This obviates…
Psychiatric Comorbidities
38 CHAPTER Psychiatric Comorbidities Sarah K. Rivelli Approximately half of all patients with epilepsy have psychiatric symptoms or disorders. Psychiatric comorbidity is an important predictor of health and quality of…
First-Generation Antiepileptic Drugs
26 CHAPTER First-Generation Antiepileptic Drugs José E. Cavazos The first-generation antiepileptic drugs (AEDs), often known as traditional AEDs, marked a significant advance in epilepsy therapy. Before the introduction of phenobarbital,…
Stimulation Therapy
30 CHAPTER Stimulation Therapy William B. Gallentine Despite the addition of numerous new antiepileptic drugs (AEDs) over the past 20 years, a substantial number of patients with epilepsy (approximately 35%)…
