10.1055/b-0034-79094 Inheritable Genetic Variations Predisposing to CNS TumorsJonathan L. Finlay and Uri Tabori Cancer is a genetic disease. However, not all cancers are inherited, and although some genetic variations predisposing…
10.1055/b-0034-79097 Critical CareNathan Dean The pediatric intensive care unit (PICU) is a multidisciplinary region of the hospital designed to care for patients with impending and current single or multiorgan failure….
10.1055/b-0034-79101 ChemotherapyEugene I. Hwang, Lindsay B. Kilburn, and Brian R. Rood The addition of chemotherapy to regimens that previously utilized only surgery and/or radiation has significantly improved the survival for…
10.1055/b-0034-79096 Surgical Strategies and the Pursuit of MinimalismRobert F. Keating The past few decades have seen successive quantum leaps forward in the surgical arena known as neurosurgery. Although the basic…
10.1055/b-0034-79093 Cytogenetic/Molecular Biology: Recent Advances in the Cytogenetics and Molecular Biology of Pediatric Brain TumorsJong Hee Chang, Yuzo Terakawa, Christian A. Smith, and James T. Rutka Brain tumors are the…
10.1055/b-0034-79092 NeuropathologyMariarita Santi and Elisabeth J. Rushing Since 1979, tumors of the central nervous system (CNS) have been classified according to guidelines promulgated by the World Health Organization (WHO), which…
10.1055/b-0034-79095 Anesthesia ConsiderationsThalia C. Palmer Among solid tumors, those affecting the brain are the primary cause of death in children. Notably, the incidence of both primary and metastatic brain tumors…
10.1055/b-0034-79088 Pediatric Neuro-Oncology: A Historical PerspectiveJames Tait Goodrich Cancer has been called “the emperor of all maladies” by Siddhartha Mukherjee, a well-known oncologist.1 This chapter discusses the development of the…
10.1055/b-0034-79090 Neurodiagnostic PrinciplesCourtney A. Lyle and John R. Crawford A comprehensive neurologic examination plays a crucial role in the diagnosis and ongoing management of children with brain tumors. The presenting…
10.1055/b-0034-79089 EpidemiologyGreta Bunin Epidemiology of Childhood Brain Tumors Little is known about the etiology of brain tumors in children. Epidemiologists have applied their methods to uncover risk factors, but small…
