INTRODUCTION Print Section Listen There are four major categories of idiopathic inflammatory myopathy: dermatomyositis (DM), polymyositis (PM), immune-mediated necrotizing myopathy (IMNM), and inclusion body myositis (IBM), which are clinically, histologically,…
INTRODUCTION Print Section Listen Numbness, pain, and/or weakness involving one or both arms are common reasons for referral to the neuromuscular clinician. These symptoms may be due to radiculopathy, brachial…
INTRODUCTION Print Section Listen This chapter describes the disorders of neuromuscular transmission (DNMT) other than myasthenia gravis (MG) (Table 26-1). The neuromuscular junction (NMJ) is a physiologically complex structure. Its…
INTRODUCTION Print Section Listen We define “neuromuscular mimic” as any musculoskeletal condition that presents with pain and apparent weakness, and can mimic a neuromuscular etiology such as radiculopathy or entrapment…
INTRODUCTION Print Section Listen In this chapter, we describe the pathophysiology, clinical presentation, laboratory findings, and treatment of the nondystrophic myotonias and periodic paralyses (Table 31-1). There are several inherited…
INTRODUCTION Print Section Listen Limb pain, diminished sensation (numbness), altered sensory perception (paresthesias and dysesthesias) and impaired function due to weakness are exceedingly common complaints in the practice of medicine….
INTRODUCTION Print Section Listen The inherited metabolic myopathies are traditionally classified by their underlying biochemical abnormalities as disorders of (1) carbohydrate, (2) lipid, and (3) adenine nucleotide metabolism. A fourth…
INTRODUCTION Print Section Listen Hereditary neuropathies may account for as many as 50% of previously undiagnosed peripheral neuropathies referred to large neuromuscular centers. Charcot–Marie–Tooth (CMT) disease is the most common…
INTRODUCTION Print Section Listen This chapter describes the disorders of neuromuscular transmission (DNMT) other than myasthenia gravis (MG) (Table 26-1). The neuromuscular junction (NMJ) is a physiologically complex structure. Its…
INTRODUCTION Print Section Listen Acquired, autoimmune myasthenia gravis (MG), the most common noniatrogenic disorder of neuromuscular transmission (DNMT), remains the favorite child of many neuromuscular clinicians. Arguably, it provides more…
