Abstract Depending on the extent of neuromuscular deficits, interventions to improve or restore upright mobility to persons paralyzed from central nervous system (CNS) disorders can include bracing, neuroprostheses employing surface…
Abstract Neuroprostheses can be used to move paralyzed limbs through the coordinated electrical activation of multiple muscles. Specifically, implantable motor neuroprostheses are used to provide hand grasping and reach for…
Abstract Ischemic stroke is a leading cause of permanent disability worldwide. While intensive rehabilitation has the potential to improve motor function in some patients in the chronic phase of stroke,…
Abstract Neuroimaging studies in patients with depression have been critical in identifying a network of brain regions involved in the symptomatology and treatment of depression. Since a substantial proportion of…
Abstract This chapter reviews the therapeutic and neuroprosthetic applications of functional electrical stimulation (FES) among stroke survivors. There is growing evidence that therapeutic applications of surface and intramuscular FES are…
Abstract The economic and societal burden of treatment-resistant depression, which comprises 12%–20% of all depressed patients, remains a significant challenge to the psychiatric and neurosurgical communities. Cortical stimulation, in its…
Abstract The history of neuromuscular electrical stimulation has been well documented. Depending upon how far back in time one chooses to go, it is clear that the field has a…
Abstract Transcranial magnetic-resonance-guided focused ultrasound surgery (MRgFUS) has recently received attention as a novel noninvasive therapeutic option that can be applied as an alternative to the established neurosurgical interventions in…
Abstract Addiction is associated with enormous individual distress and tremendous socioeconomic consequences, and remains one of the most challenging health problems of today. Unfortunately, pharmacological, psychological, and social interventions often…
Abstract Epilepsy is a chronic seizure condition, classically characterized as “a continuing tendency to seizure relapse” (Shorvon and Goodridge, 2013). It was estimated to affect 50 million people worldwide in…
