Stroke Unit
Fig. 2.1 Stroke unit. Interior view of stroke unit (a); exterior (b) and interior (c) view of mobile stroke unit. Reproduced by permission of Business Wire (University of Tennessee Web…
NEUROLOGY
Intravenous Thrombolysis for Acute Ischemic Stroke
Fig. 6.1 History of clinical trials of IV thrombolysis Finally, following the publication of the ECASS-III study in 2008, the time window for administration of intravenous (IV) thrombolysis was expanded…
Overview of Patient Management Flow
Fig. 4.1 A schematic diagram showing patient management flow (CT computed tomography, MRI magnetic resonance imaging, IV intravenous, IA intra-arterial) 4.1 Care in the Emergency Unit Treatment of suspected stroke…
Use of Advanced Neuroimaging (fMRI, DTI/Tractography) in the Treatment of Malignant Gliomas
Fig. 1.1 Hand motor fMRI activation in a patient with two contrast enhancing tumors that both displace the motor gyrus and efface the central sulcus. The red line indicates the position…
Fluorescence-Guided Resection of Malignant Gliomas
Fig. 6.1 Scheme illustrating the nature of fluorescence and how it is visualized A Brief History Historically, the use of a fluorophore for highlighting malignant glioma tissue was first described by…
The Role of Laser-Induced Thermal Therapy in the Management of Malignant Gliomas
Fig. 7.1 MRI-compatible surgical suite at Yale New Haven Hospital. Patient positioning and preparation prior to obtaining pre-LITT MRI. Heat delivery is performed under MRI guidance for intra-procedural monitoring and confirmation…
The Usefulness of Stereotactic Neuronavigation Along with Intraoperative Imaging in Malignant Brain Tumor Surgery
Fig. 4.1 Intraoperative use of ultrasound revealing a hyperechoic lesion representing tumor prior to resection. A hypoechoic area in the center is the carotid artery. The apparatus remains on the field…
Personalized Medicine Through Advanced Genomics
Fig. 3.1 Cost of sequencing a single human genome. Sequencing costs have fallen rapidly over the past five years as next-generation technologies become increasingly efficient. Graph is reproduced using data from…
Molecular Neuropathology and the Ontogeny of Malignant Gliomas
Fig. 2.1 The panels display the new ‘layered’ approach to the diagnosis of malignant gliomas as suggested by the ‘ISN (International Society of Neuropathology) Haarlem consensus guidelines’ and revised World Health…
Radiation Therapy for Malignant Gliomas: Current Options
No patients Histology Extent of resection Median overall survival by group (months) Supportive care (mo) Chemoa (mo) Radiationb (mo) ChemoRTa (mo) BTSG 69–01 [13] (1978) 303 90% GBM, 9%…
