Fig. 1 Representative immunofluorescence images of myelinating cultures (28 DIV). (a) Two colour immunofluorescence microscopy reveals the presence of a dense bed of neurites (Red; neurofilament-specific antibody SMI31) and myelinating…
Fig. 1 Schematic illustration of the electrochemiluminescence NfL immunoassay. The carbon ink electrodes are coated with the capture mAB 47:3. The biotinylated detection mAB 2:1 binds to SULFO-TAG labelled streptavidin,…
Fig. 1 Principle of ELISPOT. For cytokine ELISPOT assay, the membrane of an ELISPOT plate is coated first with capture antibody as shown in (a). (b) Cytokines that are produced…
Fig. 1 Isolation of CNS infiltrating cells from C57Bl/6 mice with EAE. (a) Absolute numbers of live and CD90 positive cells. Data represents CNS isolated material from 19 EAE diseased…
Fig. 1 cEEG demonstrating NCSE only detected with depth electrodes (D leads) in a 59-year-old woman with refractory status epilepticus despite pentobarbital, midazolam, levetiracetam, valproate, and phenytoin. Note the relative…
Fig. 1 Extreme delta brush pattern (arrow) and seizure onset in a patient with NMDA encephalitis Patients with antibodies to the leucine-rich glioma-inactivated 1 (LGI1) protein component of the voltage-gated…
Stage 1: early SE Seizure lasting 5 min or two or more seizures without recovery of consciousness between Stage 2: established SE Ongoing SE after appropriately dosed benzodiazepine Stage 3:…
Fig. 1 One-hour QEEG panel and corresponding raw EEG. (a) Example of a QEEG panel consisting of the following QEEG tools: rhythmicity spectrogram (displayed for the left and right hemispheres),…
Fig. 1 ECG artifact. In this low-voltage EEG, the artifact generated by a brief run of ventricular tachycardia can easily be mistaken for generalized periodic discharges Pulse artifact is another…
Fig. 1 Algorithm for calculation of AEEG. The raw EEG is filtered, rectified, smoothed, and the amplitude displayed as a range on a combined linear/logarithmic compressed time scale AEEG has…
