Figure 13.1 Atrophy pattern in patients with lvPPA variants versus controls. This statistical parametrical mapping depicts patterns of gray matter atrophy in patients with logopenic variant compared to healthy controls…
Figure 16.1 Common structural neuroimaging features of non-amnestic mild cognitive impairment subtypes. Dysexecutive MCI. An 80-year-old man with hypertension, chronic tobacco use, and emphysema presented with new persistent mental rigidity…
Figure 8.1 Protein and functional imaging in Alzheimer’s disease. (A) Pittsburgh compound B (PIB) binds to brain amyloid in a patient clinically diagnosed with Alzheimer’s disease (AD) compared with a…
html xmlns=”http://www.w3.org/1999/xhtml” xmlns:mml=”http://www.w3.org/1998/Math/MathML” xmlns:epub=”http://www.idpf.org/2007/ops”> Chapter 11 The non-fluent/agrammatic variant of primary progressive aphasia Murray Grossman The Behavioral Neurology of Dementia, 2nd edn, ed. Bruce Miller and Bradley Boeve. Published by…
html xmlns=”http://www.w3.org/1999/xhtml” xmlns:mml=”http://www.w3.org/1998/Math/MathML” xmlns:epub=”http://www.idpf.org/2007/ops”> Chapter 9 Frontotemporal dementia Shirley Y. Pang and Bruce L. Miller The Behavioral Neurology of Dementia, 2nd edn, ed. Bruce Miller and Bradley Boeve. Published by…
Fig. 16.1 Schematic of experimental design. Shown are the steps using phMRI to identify common brain activity in drugs at risk, and those for treating suicidal ideation and self-harm. Finding the…
Fig. 3.1 Regulatory history and perspectives on SIB assessment. a 1991–2008 b 2009–2013 European Regulators were the first to post restrictions on the use of antidepressants. In 2003, the UK Medicines…
Fig. 2.1 Public health burden of suicidal behavior among adults aged ≥18 years—United States, 2008 (Source Crosby et al. 2011). *Source CDC’s National Vital Statistics System. All rates per 100,000 population. § Agency…
Validity Description Challenges Face The animal model should recapitulate one or more of the core symptoms of the disease Difficult to replicate the features of suicide in a non-human species…
Fig. 4.1 Suicidal ideation and behavior categories and definitions (FDA 2012) Suicidal ideation and a history of suicidal behavior are among the most salient short- and long-term risk factors for suicide…
