Deprivation Therapy for Depression
Kasper S, Sack DA, Wehr TA, Kick H, Voll G, Vieira A (1988) Nocturnal TSH and prolactin secretion during sleep deprivation and prediction of antidepressant response in patients with major…
NEUROLOGY
Restricted or Disrupted Sleep as a Causal Factor in the Development of Depression
Fig. 1 Overview of potential mechanism through which chronically restricted and disrupted sleep may contribute to the development and maintenance of depression. Green arrow indicates a mild positive effect of restricted…
Arousal, and Sleep
Fig. 1 REM sleep parameters plotted as 20 h totals for baseline (Base), two shock training days (ST1, ST2), and context (Con) in a study comparing the effects of controllable (modeled by…
and Plasticity in Schizophrenia
Two or more of the following present for at least one month (less if treated) Positive symptoms (at least one) • Delusions • Hallucinations • Disorganized speaking and thinking •…
Studies on the Role of Sleep in Memory: From Behavioral Performance to Molecular Mechanisms
Fig. 1 Three distinct stages of memory as illustrated by two commonly used learning paradigms. Panel a shows the three different stages of memory for contextual fear conditioning . Rodents are…
Memory Consolidation in Healthy Aging and Mild Cognitive Impairment
Diekelmann S, Wilhelm I, Born J (2009) The whats and whens of sleep-dependent memory consolidation. Sleep Med Rev 13:309–321PubMed Dijk DJ, Duffy JF, Czeisler CA (2000) Contribution of circadian physiology…
Deprivation and Gene Expression
Fig. 1 Effects of sleep deprivation on plasticity-related gene expression. Symbols indicate different sleep deprivation methods, brain areas, targets of detection assays, and animal models used (respectively, polygons in red, green,…
Inborn Errors of Metabolism
Disease OMIM Protein/gene Main clinical symptoms MRI Prognosis [OMIM] Isovaleric aciduria 243500 Isovaleryl CoA dehydrogenase- IVD Acute: feeding refusal or aversion to protein, lethargy evolving to coma (due to dehydration…
Leukodystrophies
Fig. 14.1 Cerebral form of X-linked adrenoleukodystrophy, c-ALD. MRI axial T2-weighted images (a, b) show marked bilateral symmetrical hyperintensity in the splenium of the corpus callosum and in the adjacent…
Myelin Disorders: Multiple Sclerosis
Fig. 11.1 MS, acute phase. T2-weighted image, (a, c) demonstrate focal hyperintensities in the left pons and in the white matter of the right hemisphere, respectively; note, edema around the…
