Acknowledgments The authors would like to acknowledge our colleagues and teachers in neuroradiology at the University of Pennsylvania for their insights on brain tumor imaging, particularly Drs Ronald Wolf, Linda…
Standard-of-care radiation regimens Historical Context of Radiation Therapy and Dose Historically, standard treatment for glioblastoma (GBM) was surgical resection alone. The first randomized trial to show a survival benefit with…
Introduction Glioblastoma (GBM), the most common primary brain malignancy, carries a poor prognosis and has therefore been the subject of numerous studies attempting to improve outcomes. Although a plethora of…
Introduction This chapter reviews the history of angiogenesis and how it was recognized as an essential mechanism for tumor establishment and growth. From the initial recognition of tumor vascularity to…
1 Cerebrovascular Anatomy and Implications for Arteriovenous Malformation Treatment W. Caleb Rutledge and Michael T. Lawton Abstract Arteriovenous malformations (AVMs) are complex vascular lesions. The Spetzler–Martin system and Lawton–Young supplementary grading…
26 Radiosurgery for Dural Arteriovenous Fistulas: Indications and Outcomes Cheng-Chia Lee, Huai-Che Yang, Hsiu-Mei Wu, Wen-Yuh Chung, Wan-Yuo Guo, and David H.C. Pan Abstract Stereotactic radiosurgery using the Gamma Knife or…
15 Surgical Treatment of Cerebellar Arteriovenous Malformations João Paulo Almeida, Vitor Yamaki, Mateus Reghin Neto, Feres Chaddad Neto, Albert Rhoton Jr., and Evandro de Oliveira Abstract Cerebellar arteriovenous malformations (AVMs) represent…
13 Step-by-Step Microsurgical Resection of Arteriovenous Malformations Benjamin K. Hendricks and Aaron Cohen-Gadol Abstract Cerebral arteriovenous malformations (AVMs) represent a highly morbid and formidable neurosurgical challenge. Cerebral AVMs are managed with…
31 Epilepsy Management for Arteriovenous Malformation Mark Quigg Abstract About one-third of patients with arteriovenous malformation (AVM) present with seizures, and about 40% of those will have AVM-related epilepsy (AVMRE). Seizures…
28 Treatment of Inoperable Cerebral Arteriovenous Malformations Marshall C. Cress, Jason M. Davies, and Elad I. Levy Abstract This chapter on the treatment of “inoperable” arteriovenous malformations (AVMs) critically evaluates what…
