Hypotheses on Treatment Prediction with Positional Therapy 1. Calculated Non-supine AHI According to the first hypothesis, the calculated baseline non-supine AHI is equal to the actual AHI with positional therapy….
Fig. 1 POSA percentages with results from Mador et al. [7] and unpublished data Sint Lucas Andreas Ziekenhuis (SLAZ) Various Theories Different studies support the statement that patients with POSA…
A → The presence of one or more of the following applies: i. The patient complains of sleepiness, nonrestorative sleep, fatigue, or insomnia symptoms. ii. The patient wakes with breath holding, gasping,…
Fig. 1 Percentage of the total sleeping time (TST) spent in supine position and an apnea-hypopnea index (AHI) of a patient with mild OSA Figure 1 depicts a very archetypal…
Characteristics Mean ± SD Age 43.0 ± 13.04 BMI 27.18 ± 5.26 Neck circumference (cm) 37.64 ± 3.05 AHI 2.13 ± 1.44 Sleep efficiency (%) 87.90 ± 10.01 Total sleep time (min) 440.29 ± 3.79 SD standard deviation, BMI body mass index, AHI apnea-hypopnea…
Fig. 1 Flowchart for the APOC. The red boxes show the best possible outcome for these patients with successful positional therapy (PT). AHI apnea-hypopnea index, APOC Amsterdam positional OSA Classification,…
Fig. 1 Orexin neurons expresses adenosine A1 receptors as evident by double labelled fluorescence. Panel a Orexin-A containing neurons in the perifornical region (green fluorescence). Panel b Same visual field and…
Fig. 1 Gamma aminobutyric acid (GABA A ) modulators (eszopiclone and zolpidem) dose-responsively alter electroencephalogram (EEG) spectral frequency of sleep/wake states in inactive-phase dosing, whereas DORA-22 produces sleep more akin to…
Fig. 1 Sleep state abnormalities in orexin receptor knockout mice. Representative 12-h dark-period (20:00–08:00) hypnograms for wild-type (WT), OX1R −/−, OX2R −/−, and OX1R −/−; OX2R −/− mice, all with a…
, A. Imanishi1, Y. Ohmori1, Y. Sagawa1, Y. Takahashi1 , M. Omokawa1, M. Sato1, Y. Hishikawa1, T. Shimizu1, 2 and S. Nishino3 (1) Department of Neuropsychiatry, Akita University School of Medicine, Akita, Japan (2) International Institute for Integrative Sleep Medicine…
