Multiple sclerosis

Jun 19, 2016 by in NEUROLOGY Comments Off on Multiple sclerosis

Chapter 14 Multiple sclerosis Chapter contents Demyelination Clinical features of MS Diagnosis and management Pathological features Aetiology Pathogenesis Neurodegeneration in MS Multiple sclerosis is an inflammatory demyelinating disease of the…

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Cellular mechanisms of neurological disease

Jun 19, 2016 by in NEUROLOGY Comments Off on Cellular mechanisms of neurological disease

Chapter 8 Cellular mechanisms of neurological disease Chapter contents Neuronal injury and death Cell death mechanisms Inflammation and gliosis Neurodegeneration Prion diseases The nervous system is subject to the full…

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Neurons and glial cells

Jun 19, 2016 by in NEUROLOGY Comments Off on Neurons and glial cells

Chapter 5 Neurons and glial cells Chapter contents Nerve cells Astrocytes Oligodendrocytes and Schwann cells Other glial cells Glial tumours Nerve cells The basic structure of the neuron has been…

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Electrical signalling in neurons

Jun 19, 2016 by in NEUROLOGY Comments Off on Electrical signalling in neurons

Chapter 6 Electrical signalling in neurons Chapter contents The neuron at rest Excitability The action potential Axonal conduction Neurons are excitable cells, meaning that they respond to stimulation and can…

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Sensory and motor pathways

Jun 19, 2016 by in NEUROLOGY Comments Off on Sensory and motor pathways

Chapter 4 Sensory and motor pathways Chapter contents Spinal segments Somatic sensory pathways Somatic motor pathways Lower motor neurons Reflexes and muscle tone The central nervous system contains a large…

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Head injury

Jun 19, 2016 by in NEUROLOGY Comments Off on Head injury

Chapter 9 Head injury Chapter contents Clinical aspects Pathology of head injury Brain swelling and intracranial pressure Minor head injury In the UK, trauma is the leading cause of death…

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Development of the brain

Jun 19, 2016 by in NEUROLOGY Comments Off on Development of the brain

Chapter 2 Development of the brain Chapter contents Neural tube formation Divisions of the brain Ventricular system Neural tube formation The central nervous system is derived from the neural tube,…

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Synaptic transmission

Jun 19, 2016 by in NEUROLOGY Comments Off on Synaptic transmission

Chapter 7 Synaptic transmission Chapter contents General principles Neurotransmitters Postsynaptic receptors Synaptic integration General principles The majority of synapses in the brain and spinal cord are chemical, meaning that the…

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