Figure 52-1 Sural nerve biopsy from a patient with peripheral neuropathy after bariatric surgery demonstrating very active axonal degeneration. Teased fiber preparations (upper left) show almost all fibers are undergoing…
Figure 50-1 Selected microscopic fields from sural biopsy from the patient presented. The upper frame is a paraffin section stained with hematoxylin and eosin that demonstrates a giant cell (arrow)…
Figure 44-1 Cross-section of right sural nerve biopsied at ankle level. Nerve conduction studies of this nerve performed 1 week before biopsy were within normal limits. This methylene blue–stained semithin…
Figure 19-1 Serial transverse paraffin sections. A, Hematoxylin and eosin section demonstrates multiple whorl-like structures corresponding to microfascicles (arrow) replacing the normal architecture of the nerve. Note one preserved nerve…
Figure 26-1 Pes cavus, right toe drop, wasting of intrinsic hand muscles, hyperpigmented scars and joint creases. Figure 26-2 Mucosal pigmentation, best seen at the side of the tongue. Nerve…
Figure 40-1 Right ulnar motor inching study across the elbow region recording from the abductor digiti minimi muscle. Stimulation sites of successive potentials (from top to bottom) are listed in…
Figure 38-1 Sural nerve features. A, Considerable reduction in myelinated nerve fiber density. Few axons with disproportionately thin myelin sheaths, minor onion bulb formation (black arrows). Sporadic nerve fibers with…
CONCLUSION CMT-4C is an extremely rare autosomal recessive demyelinating motor sensory neuropathy. Thus far, a little more than 60 cases have been reported in the literature.3–5 In addition to the…
Figure 33-1 Sural nerve biopsy. Paraffin-embedded longitudinal section stained with an antitransthyretin antibody. Amorphous deposits labeled by the antibody are present in the endoneurium, sometimes in perivascular regions (arrow) or…
Figure 32-1 Amyloid depositions (arrows) in endoneurium and vessel walls illustrated by Congo-red stain (top left) showing apple green birefringence under polarized light (top right), H&E stain (bottom left), methylviolet…
