10 Venous Thromboembolism (DVT and PE): Diagnosis and Treatment Graham F. Pineo and Mark G. Hamilton Definition Deep vein thrombosis (DVT) most commonly involves the deep veins in the lower…
15 Postoperative Strategies for Resumption of Anticoagulants and Antiplatelet Agents in Neurosurgical Patients Douglas W. Sborov and George M. Rodgers Intracranial and spine surgeries are associated with a high risk…
12 Role of Anticoagulants in Common, Nonneurosurgical, Non-VTE Conditions Christian A. Bowers and Robert C. Pendleton Arterial and venous thrombotic events combined, which include acute coronary syndromes, stroke, peripheral arterial…
24 Intraoperative Cranial-Specific Patient/Case Examples Mark G. Hamilton, John G. Golfinos, Graham F. Pineo, and William T. Couldwell Management of patients undergoing cranial surgery involves all aspects of coagulation and…
26 Intraoperative Spine Surgery–Specific Patient/Case Examples W. Bradley Jacobs Both intraoperative hemostasis and coagulation management as well as postoperative venous thromboembolism (VTE) prophylaxis are crucial aspects of appropriate spine surgical…
22 Neuroendovascular-Specific Patient/Case Examples Alim P. Mitha, Michael Tso, Felipe C. Albuquerque, Cameron G. McDougall, and John H. Wong Anticoagulation management is an important aspect of endovascular neurosurgical interventions. This…
19 Risk of Anticoagulants and Antiplatelet Agents in Common Neurovascular Conditions Benjamin W.Y. Lo and R. Loch Macdonald There is a paucity of high-level evidence (lack of prospective studies) investigating…
2 Coagulation and Platelet Plug Formation George M. Rodgers Hemostasis mechanisms prevent excessive blood loss after vascular injury while also preventing an inappropriate thrombotic response. This equilibrium is maintained by…
3 Preoperative Coagulation Assessment for the Neurosurgical Patient Venkatesh K. Rudrapatna and George M. Rodgers Evidence-Based Background When a blood vessel is injured, the vascular, platelet, coagulation, and fibrinolytic systems…
7 Principles of Blood Loss Tsinsue Chen, Rami O. Almefty, and Peter Nakaji Blood loss, a universal concern in surgery, is only somewhat mitigated by the possibility of blood replacement…
